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Related Experiment Video

Updated: Mar 20, 2026

Non-restraining EEG Radiotelemetry: Epidural and Deep Intracerebral Stereotaxic EEG Electrode Placement

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Published on: June 25, 2016

Status epilepticus in scrub typhus.

Jayantee Kalita¹, Vinita E Mani¹, Sanjeev K Bhoi¹

¹Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.

|May 25, 2016

Summary

Status epilepticus (SE) can occur in scrub typhus patients, with 15% experiencing this neurological complication. Fortunately, scrub typhus-related SE shows a good prognosis and complete recovery with appropriate treatment.

Keywords:

Antiepileptic drugs EEG Infection Scrub typhus Status epilepticus

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Published on: November 8, 2018

Area of Science:

Infectious Diseases
Neurology
Critical Care Medicine

Background:

Scrub typhus is an emerging infectious disease with limited data on neurological complications like status epilepticus (SE).
Understanding the clinical presentation and outcomes of SE in scrub typhus is crucial for patient management.

Purpose of the Study:

To describe the clinical spectrum and outcomes of status epilepticus in patients with scrub typhus.
To evaluate the efficacy of antiepileptic drugs and long-term prognosis for SE in this population.

Main Methods:

A 3-year prospective observational study included scrub typhus patients diagnosed with SE.
Data collected included demographics, clinical features, neuroimaging (CT, MRI), electroencephalography (EEG), and response to antiepileptic drugs (AEDs).
Outcomes were assessed at 1 month and 1 year post-treatment.

Main Results:

Out of 66 scrub typhus patients with central nervous system involvement, 10 (15.2%) presented with SE.
The median age was 34 years, and SE duration varied significantly (10 min to 48 h).
Most patients responded to one or two AEDs, with normal cranial MRI findings and complete recovery by 1 month with doxycycline.

Conclusions:

Status epilepticus is a notable neurological complication in scrub typhus, affecting approximately 15% of CNS-involved cases.
Despite SE, scrub typhus patients demonstrate a favorable prognosis with complete recovery and successful AED withdrawal.
Early diagnosis and treatment of scrub typhus are key to managing SE and ensuring good patient outcomes.