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Membrane phase characteristics control NA-CATH activity.

Robin Samuel1, Susan Gillmor1

  • 1Department of Chemistry, George Washington University, Washington, DC 20052, United States.

Biochimica Et Biophysica Acta
|May 25, 2016
PubMed
Summary

NA-CATH, a snake antimicrobial peptide, effectively targets bacteria by altering its membrane interaction mechanism. Its activity shifts between membrane disruption and pore formation based on lipid composition and phase, influencing bacterial lysis kinetics.

Keywords:
AMPAmphipathic helixAnd fluorescence requenchingAntibacterialAntimicrobialNA-CATHProtein-liposome interaction

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