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Updated: Mar 20, 2026

Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection
Published on: August 26, 2011
[Autobiographical memory and self-disorders in schizophrenia].
F Berna1, J Potheegadoo2, M C Allé2
1Pôle de psychiatrie, santé mentale et addictologie, hôpitaux universitaires de Strasbourg, 1, place de l'Hôpital, BP 426, 67091 Strasbourg cedex, France; Inserm U1114, 1, place de l'Hôpital, BP 426, 67091 Strasbourg cedex, France; Université de Strasbourg, fédération de médecine translationnelle de Strasbourg, 67412 Illkirch cedex, France.
Schizophrenia patients exhibit less specific autobiographical memories and altered self-images, impacting their sense of self. Cognitive remediation and psychotherapy targeting autobiographical memory may improve self-coherence and stability in these patients.
Area of Science:
- Cognitive Neuroscience
- Psychopathology
- Memory Research
Background:
- Disorders of self are a core feature of schizophrenia, historically understood through philosophical lenses.
- Recent research explores cognitive mechanisms underlying these self-disorders.
Purpose of the Study:
- To investigate how autobiographical memory deficits may explain self-disorders in schizophrenia.
- To examine the relationship between autobiographical memory and the self using the Self-Memory System model.
Main Methods:
- Theoretical literature review of autobiographical memory studies in schizophrenia.
- Application of the Self-Memory System model, distinguishing working-self and autobiographical memory knowledge base.
- Analysis of phenomenological and conceptual aspects of self and memory.
Main Results:
- Schizophrenia patients show less specific autobiographical memories with fewer phenomenological details.
- Impaired mental time travel, reduced self-coherence, and unstable self-images are observed.
- Weakened connections between self-images and autobiographical memories, and disorganized reminiscence bumps are evident.
Conclusions:
- Autobiographical memory deficits are linked to altered phenomenological and conceptual dimensions of the self in schizophrenia.
- Cognitive remediation and psychotherapy targeting autobiographical memory show therapeutic potential.
- These interventions may enhance self-retrieval, coherence, and stability in patients.
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