Related Experiment Video
Updated: Sep 3, 2026

08:26
Assessing Activity-based Anorexia in Mice
Published on: May 14, 2018
[Effect of starvation on respiratory reactivity in inbred rats]
Abstract:
The 5-day starvation, with water ad libitum, decreased the reactivity of the respiration system to acute hypoxic hypoxia (11% O2) in spontaneously hypertensive (SH) rats and had no such effect in Krushinskiĭ-Molodkina (KM) rats. The difference in the responses of KM and SH rats to starvation and the action of hypoxic gas mixture shows that the respiratory system reactivity has an obvious genetic component.
Related Concept Videos
Factors Affecting Respiration
Respiration is a crucial physiological function involving exchanging oxygen (O2) and carbon dioxide (CO2) between an organism and its environment. Various factors can impact this essential process:
Chemical Factors Affecting Respiration Centers
Chemical factors such as changing CO2, O2, and H+ levels in arterial blood play a critical role in influencing respiration depth and rates. These variations are detected by chemoreceptors—specialized sensors located in two primary body areas. Central chemoreceptors are found throughout the brain stem, including the ventrolateral medulla, while peripheral chemoreceptors are located in the aortic arch and carotid arteries.
CO2 has a potent influence on respiration and is strictly regulated. Under...
CO2 has a potent influence on respiration and is strictly regulated. Under...
Acute Respiratory Failure-II
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:

