[Issues in Coronary Artery Bypass Grafting for Kawasaki Disease]
Shintaro Katahira1, Shunsuke Kawamoto, Katsuhiro Hosoyama
1Division of Cardiovascular Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Insights
Coronary artery bypass grafting (CABG) for Kawasaki disease (KD) complications can have long-term issues. Careful preoperative evaluation is key to improving surgical outcomes for KD patients with coronary artery aneurysms.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
- Rheumatology
Background:
- Kawasaki disease (KD) can lead to progressive coronary artery narrowing and aneurysms.
- Surgical intervention, such as coronary artery bypass grafting (CABG), is sometimes necessary for advanced KD coronary artery disease.
- Long-term outcomes and challenges following CABG in KD patients require further elucidation.
Observation:
- A cohort of 6 patients underwent CABG for KD-related coronary artery lesions between 2000 and 2013.
- No operative mortality was observed.
- Follow-up averaged 5 years, with 2 patients experiencing cardiac events.
Findings:
- One patient experienced left internal thoracic artery (LITA) graft occlusion due to flow competition.
- Another patient required re-do CABG due to graft occlusion at coronary artery aneurysms.
- These events highlight potential long-term complications after CABG in KD patients.
Implications:
- Meticulous preoperative diagnostic evaluation of coronary artery aneurysms is crucial.
- Improved preoperative assessment may enhance long-term outcomes for KD patients undergoing surgical intervention.
- Further research is needed to optimize management strategies for post-KD coronary artery disease.
Abstract:
Progressive narrowing at the entrance and exit of coronary artery aneurysm can develop at late phase of Kawasaki disease (KD). Evaluation and prediction of progressive coronary lesions remain a challenge in the treatment of post-KD coronary artery disease. We aimed to elucidate long-standing issues imposed on the patients who underwent coronary artry bypass grafting (CABG) for coronary artery lesions associated with KD. Between January, 2000 and December, 2013, CABG for coronary artery lesions associated with KD were performed in 6 patients (male/female: 5/1, mean age 14.5±10.0). There was no operative mortality. Follow-up for the 6 patients has been performed with the average period of 5 years (1~9 years). Cardiac events occurred in 2 patients during follow-up. In 1 patient, left internal thoracic artery (LITA) occluded due to flow competition between the native artery and LITA graft after LITA to LAD bypass grafting. The other patient required a re-do CABG using the free right internal thoracic artery to the circumflex branch because of occlusion at the coronary artery aneurysms after 4 years postoperatively. Meticulous preoperative diagnostic evaluations of coronary artery aneurysm may further improve the long-term outcome after surgical intervention for coronary lesions in conjunction with an aneurysm.
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