Good Clinical Outcomes in Budd-Chiari Syndrome with Hepatic Vein Occlusion

Xinxin Fan1, Kai Liu1, Yuan Che1

  • 1Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, 305 East Zhongshan Road, Nanjing, 210002, Jiangsu Province, People's Republic of China.

Insights

Hepatic vein angioplasty and transjugular intrahepatic portosystemic shunt (TIPS) offer effective treatment for Budd-Chiari syndrome (BCS) with hepatic vein occlusion. These interventions demonstrate excellent long-term outcomes for patients suffering from this condition.

Area of Science:

  • Interventional Radiology
  • Hepatology
  • Vascular Surgery

Background:

  • Budd-Chiari syndrome (BCS) with hepatic vein (HV) occlusion presents with severe liver damage in acute cases.
  • Chronic BCS can lead to esophageal variceal bleeding or refractory ascites, mimicking cirrhotic portal hypertension.

Purpose of the Study:

  • To assess the clinical efficacy and safety of HV angioplasty and transjugular intrahepatic portosystemic shunt (TIPS) for treating BCS.
  • To evaluate these interventional procedures in patients experiencing HV occlusion.

Main Methods:

  • A study involving 60 patients with HV occlusive BCS between May 1995 and December 2014.
  • Procedures included HV angioplasty, combined HV and IVC angioplasty, TIPS, and modified TIPS for extensive HV occlusion.

Main Results:

  • Successful interventional procedures in all 60 patients.
  • Significant reduction in portal pressure and increase in portal flow velocity post-TIPS.
  • Low rates of mortality and shunt-related complications during follow-up.

Conclusions:

  • HV angioplasty and TIPS provide excellent long-term outcomes for BCS patients with HV occlusion.
  • These minimally invasive techniques are effective in managing the complications of BCS.
Abstract

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