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Emergence of NDM-1 and OXA-72 producing Acinetobacter pittii clinical isolates in Lebanon

A Al Atrouni1, M-L Joly-Guillou2, M Hamze3

  • 1Laboratoire Microbiologie Santé et Environnement (LMSE), Ecole Doctorale des Sciences et de Technologie et Faculté de Santé Publique, Université Libanaise, Tripoli, Liban; ATOMycA, Inserm Atip-Avenir Team, CRCNA, Inserm U892, 6299 CNRS, University of Angers, France.

New Microbes and New Infections
|May 26, 2016
PubMed

Insights

The first detection of carbapenem-resistant Acinetobacter pittii in Lebanon is reported. These clinical isolates carry concerning resistance genes, bla NDM-1 or bla OXA-72.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Antimicrobial Resistance

Background:

  • Acinetobacter species are significant opportunistic pathogens causing diverse infections globally.
  • The rise of carbapenem resistance in Acinetobacter poses a major public health threat.

Observation:

  • This study reports the initial identification of Acinetobacter pittii clinical isolates in Lebanon.
  • These isolates were found to harbor specific carbapenemase genes.

Findings:

  • The detected carbapenem resistance genes include bla NDM-1 and bla OXA-72.
  • This marks the first documented occurrence of these resistance mechanisms in Acinetobacter pittii within Lebanon.

Implications:

  • Highlights the urgent need for enhanced surveillance of carbapenem-resistant Acinetobacter in the region.
  • Informs antimicrobial stewardship and infection control strategies against emerging multidrug-resistant pathogens.
Keywords:
Acinetobacter pittiiLebanonblaNDM-1blaOxa-72carbapenem resistance

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