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The APOSTEL recommendations for reporting quantitative optical coherence tomography studies.

Andrés Cruz-Herranz1, Lisanne J Balk1, Timm Oberwahrenbrock1

  • 1From the Multiple Sclerosis Center (A.C.-H., P.V., A.J.G.), Department of Neurology, University of California San Francisco; Departments of Neurology and Ophthalmology (L.J.B., A.P.), VU University Medical Centre, Amsterdam, the Netherlands; Charité-Universitätsmedizin Berlin (T.O., F.P., A.U.B.), NeuroCure Clinical Research Center; Department of Neurology (T.O., F.P., A.U.B.), Experimental and Clinical Research Center, Max Delbrueck Center for Molecular Medicine, Berlin, Germany; Department of Neurology (S.S., P.C.), Johns Hopkins University, Baltimore, MD; Center of Neuroimmunology and Department of Neurology (E.H.M.-L., P.V.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clinic of Barcelona, Spain; Eye Center (W.A.L.), University Medical Center, Freiburg, Germany; Departments of Ophthalmology (J.S.S.) and Neurology (L.B.), New York University School of Medicine, New York; Moorfields Eye Hospital and The National Hospital for Neurology and Neurosurgery (A.P.), London, UK; and Department of Neurology (P.A.), Medical Faculty, Heinrich-Heine University Düsseldorf, Germany.

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Researchers developed a 9-point checklist for reporting quantitative optical coherence tomography (OCT) studies. These consensus recommendations aim to standardize and enhance the quality of OCT research reporting.

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Area of Science:

  • Ophthalmology
  • Neuroscience
  • Biomedical Imaging

Background:

  • Quantitative optical coherence tomography (OCT) studies require standardized reporting for reliable results.
  • Current reporting practices for OCT studies lack consistency, hindering comparability and quality assessment.

Framework:

  • A consensus-based 9-point checklist was developed for reporting quantitative OCT studies.
  • The checklist covers essential aspects from study protocol and acquisition to data analysis and nomenclature.

Implementation:

  • Expert consensus from neurologists, ophthalmologists, and neuroscientists informed the recommendations.
  • The checklist addresses study protocol, acquisition device and settings, scanning protocols, funduscopic imaging, and data handling.

Implications:

  • Standardized reporting will improve the quality and consistency of quantitative OCT studies.
  • These recommendations align OCT reporting with existing biomedical research standards.
  • The protocol provides Class IV evidence and requires future updates based on evolving insights.