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Extraskeletal osteosarcoma in two dogs.

C J Schena1, R L Stickle, R W Dunstan

  • 1Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing 48824-1314.

Journal of the American Veterinary Medical Association
|May 15, 1989
PubMed
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Extraskeletal osteosarcoma (ESOS) is a rare, aggressive tumor diagnosed in two dogs affecting the spleen and jejunum. This challenging cancer has a high recurrence and metastasis rate, particularly in older male dogs.

Area of Science:

  • Veterinary Oncology
  • Canine Pathology

Background:

  • Extraskeletal osteosarcoma (ESOS) is an exceptionally rare tumor type in dogs.
  • This tumor presents significant treatment challenges due to high rates of local recurrence and metastatic disease.

Observation:

  • ESOS was diagnosed in the spleen and jejunum of two dogs.
  • Macroscopically, ESOS typically appears as a hard mass, potentially resembling calcified hematoma or myositis ossificans.
  • Radiographically, ESOS presents as a soft tissue mass with focal mineralization, distinct from adjacent bone.

Findings:

  • ESOS predominantly affects older dogs, with no specific breed predilection noted.
  • A potential predilection for male dogs was observed.
  • The etiology of ESOS remains unknown, but is hypothesized to involve malignant transformation of mesenchymal cells into osteoblasts.

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Implications:

  • This case report highlights the diagnostic and therapeutic difficulties associated with canine ESOS.
  • Further research into the pathogenesis and treatment strategies for ESOS is warranted.
  • Understanding the radiographic and macroscopic features aids in differentiating ESOS from other splenic and jejunal masses.