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Updated: Mar 20, 2026

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy rNAION
Published on: November 20, 2016
[Shock-induced ischemic optic neuropathy]
C H van Herpen1, W A C Koekkoek, R S Ramrattan
1Ziekenhuis Gelderse Vallei, afd. Intensive Care, Ede.
Background:
Shock can lead to ischemic injury of organs. Ischemic injury of the optic nerve may even cause blindness.
Case Description:
A 61-year-old female patient was admitted to ICU with septic shock. When recovering, she was only able to determine the difference between light and dark; before admission her vision was good. Ophthalmologic examination revealed slow pupillary reflexes and pale, atrophic optic discs. The diagnosis of bilateral shock-induced ischemic optic neuropathy was made. The patient was permanently blind and traumatised by her experiences during her hospital stay when her blindness was not yet recognised.
Conclusion:
Blindness caused by ischemic optic neuropathy is a rare and severe complication of shock that is usually irreversible. Early recognition is important in order to allow appropriate communication with, and approach of the patient to prevent traumatic experiences and promote rehabilitation.
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