Correction of blood drug levels for changes over the day
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1Department of Psychiatry, University of Health Sciences, Chicago Medical School, IL 60064.
Journal of Clinical Pharmacology
|March 1, 1989
Abstract:
A graph-based method is presented to compensate for the influence of variations in drug dosage schedules and blood sampling times upon the blood concentrations of drugs whose elimination half-life is between 7 and 48 hours. This method permits the clinician to interpret blood drug levels drawn at nonstandard times, and to correct blood drug levels for how the daily dose was divided. This method is expected to improve the convenience of monitoring blood drug levels.