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Updated: Mar 20, 2026
Immunohistochemistry Test for the Lyssavirus Antigen Detection from Formalin-Fixed Tissues
Published on: October 26, 2021
Immunohistochemical Detection of Chikungunya Virus Antigens in Formalin-Fixed and Paraffin-Embedded Tissues
Chun Wei Chiam1, I-Ching Sam1, Yoke Fun Chan1
1Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Abstract:
Immunohistochemistry is a histological technique that allows detection of one or more proteins of interest within a cell using specific antibody binding, followed by microscopic visualization of a chromogenic substrate catalyzed by peroxidase and/or alkaline phosphatase. Here, we describe a method to localize Chikungunya virus (CHIKV) antigens in formalin-fixed and paraffin-embedded infected mouse brain.
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