Subungual keratoacanthoma in the hand

A subungual keratoacanthoma of the thumb with a 5-year follow-up is reported. Recurrence after initial curettage necessitated amputation of the terminal phalanx as definitive treatment. The 22 subungual keratoacanthomas of the hand reported in the literature are reviewed. Although conservative treatment sparing the digit in the form of excision and curettage is recommended as the initial treatment of choice, this uncommon benign, but aggressive, lesion of the nail bed may require amputation of the involved phalanx as definitive treatment.