Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

733
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
733
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

670
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
670
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

534
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
534
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

1.3K
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An Observational Study of Afatinib 30 mg Daily in Patients With Advanced Non-Small-Cell Lung Cancer Harboring Common EGFR Mutations Treated With Afatinib.

Thoracic cancer·2026
Same author

The effectiveness of a psychoeducational intervention on health outcomes of patients undergoing haemodialysis: A randomized controlled trial.

International journal of nursing practice·2022
Same author

Robotic-Assisted Laparoscopic Ureterocalicostomy for Persistent Uretero-Pelvic Junction (UPJ) Obstruction after Failed Renal Pyeloplasty.

European urology open science·2022
Same author

Going to war on COVID-19: Mobilizing an academic nephrology group practice.

Nephrology (Carlton, Vic.)·2020
Same author

[Advances in the research of effects and regulatory mechanism of regulatory T cells in tissue injury and repair].

Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns·2019
Same author

Right Living Donor Nephrectomies: Retroperitoneoscopic vs Laparoscopic Transperitoneal Approach.

Transplantation proceedings·2018
Same journal

Analysis of the Cost of Maintaining Effective Donors and Nondonors of Organs and Tissues in Intensive Care Units.

Transplantation proceedings·2026
Same journal

Adolescence and Pediatric Heart Transplantation: Impact of Non-Adherence on Mortality: A Single-Center Experience.

Transplantation proceedings·2026
Same journal

Impact of Family-Based Care on the Outcome of Brain Death and Humanization in the Process of Multiple Organ Donation: Case Report.

Transplantation proceedings·2026
Same journal

Karnofsky Performance Status Is Associated with Patient and Graft Survival After Liver Retransplantation.

Transplantation proceedings·2026
Same journal

Evaluating CMV Risk Stratification, Donor Characteristics, and Post-Transplant Outcomes in Kidney Transplant Recipients: A Retrospective Eurotransplant Center Analysis.

Transplantation proceedings·2026
Same journal

Twenty-One Years of Insights From A Single-Center Living Kidney Donation Program.

Transplantation proceedings·2026
See all related articles

Related Experiment Video

Updated: Mar 20, 2026

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation
07:28

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation

Published on: October 11, 2024

829

Compensatory Hypertrophy After Living Donor Nephrectomy.

K W Chen1, M W F Wu1, Z Chen2

  • 1Department of Urology, National University Health System, Singapore.

Transplantation Proceedings
|May 29, 2016
PubMed
Summary
This summary is machine-generated.

Kidney donors experience significant compensatory hypertrophy, with the remaining kidney increasing by 22.4% on average after surgery. Older donors may show a reduced hypertrophic response.

More Related Videos

Author Spotlight: Enhancing Graft Viability Assessment Through Quantitative Metrics and Innovative Reservoir Systems
08:49

Author Spotlight: Enhancing Graft Viability Assessment Through Quantitative Metrics and Innovative Reservoir Systems

Published on: August 2, 2024

1.5K
Normothermic Machine Perfusion of Rat Kidneys for Transplantation
10:42

Normothermic Machine Perfusion of Rat Kidneys for Transplantation

Published on: January 27, 2026

593

Related Experiment Videos

Last Updated: Mar 20, 2026

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation
07:28

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation

Published on: October 11, 2024

829
Author Spotlight: Enhancing Graft Viability Assessment Through Quantitative Metrics and Innovative Reservoir Systems
08:49

Author Spotlight: Enhancing Graft Viability Assessment Through Quantitative Metrics and Innovative Reservoir Systems

Published on: August 2, 2024

1.5K
Normothermic Machine Perfusion of Rat Kidneys for Transplantation
10:42

Normothermic Machine Perfusion of Rat Kidneys for Transplantation

Published on: January 27, 2026

593

Area of Science:

  • Nephrology
  • Transplant Surgery
  • Radiology

Background:

  • Kidney volume is a known predictor of estimated glomerular filtration rate (eGFR) in kidney donors.
  • Compensatory hypertrophy is the remaining kidney's ability to adapt and enlarge after nephrectomy.

Purpose of the Study:

  • To quantify compensatory hypertrophy in kidney donors post-nephrectomy using CT scans.
  • To analyze factors influencing this adaptive kidney growth.

Main Methods:

  • 29 kidney donors underwent follow-up CT scans 6 months to 1 year post-surgery.
  • Remaining kidney volume was measured pre- and post-donation.
  • eGFR was calculated using the Modification of Diet in Renal Disease equation.

Main Results:

  • 79.3% of donors exhibited compensatory hypertrophy, with a mean kidney volume increase of 22.4%.
  • Mean eGFR was 68.9 mL/min/1.73 m(2) at follow-up; 24.1% had CKD grade 3.
  • Hypertrophy was not significantly associated with sex, race, surgical approach, or hypertension, but showed a trend of decrease with age.

Conclusions:

  • Healthy kidney donors commonly show significant compensatory hypertrophy.
  • Age may be a factor in the degree of compensatory hypertrophy observed post-donation.