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Should High-Frequency Ventilation in the Adult Be Abandoned?
Albert P Nguyen1, Ulrich H Schmidt2, Neil R MacIntyre3
1Department of Anesthesiology, University of California, San Diego, California.
Abstract:
High-frequency oscillatory ventilation (HFOV) can improve ventilation-perfusion matching without excessive alveolar tidal stretching or collapse-reopening phenomenon. This is an attractive feature in the ventilation of patients with ARDS. However, two recent large multi-center trials of HFOV failed to show benefits in this patient population. The following review addresses whether, in view of these trails, HFOV should be abandoned in the adult population?
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