Vitamin D level status in Thai neuromyelitis optica patients

Vitamin D status of Thai clinically isolated syndrome (CIS), multiple sclerosis (MS) and NMO/neuromyelitis optica spectrum disorders (NMOSD) patients were prospectively collected (N=130). Its associations with disability score, and disease activity were sought. Mean vitamin D levels were not significantly different (CIS, 22.18±8.2; MS, 23.41±11.9; NMO/NMOSD, 23.54±9.3ng/mL; p=0.857). Prevalence of vitamin D insufficiency and deficiency (≤30ng/mL) was 73-80%. Neither disability score nor disease activity was associated with vitamin D level. Vitamin D insufficiency was common in Thai CIS, MS, and NMO/NMOSD patients without association with disability or disease activity.