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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
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Depression predicts mortality and hospitalization in heart failure: A six-years follow-up study

Sónia Ramos1, Joana Prata1, Paulo Bettencourt1

  • 1Cardiovascular Research Unit, Faculty of Medicine, University of Porto, Portugal.

Journal of Affective Disorders
|May 29, 2016
PubMed

Insights

Depressive symptoms in heart failure (HF) patients are linked to a higher risk of death and cardiovascular hospitalizations. This 6-year study found these associations were independent of other risk factors.

Area of Science:

  • Cardiology
  • Psychiatry
  • Public Health

Background:

  • Heart failure (HF) is a significant public health concern.
  • Depressive symptoms (DS) are common in HF patients.
  • The prognostic impact of DS in HF requires further investigation.

Purpose of the Study:

  • To determine the prevalence of depressive symptoms (DS) in outpatients with HF.
  • To evaluate the association between DS and hospitalization for cardiovascular (CV) causes.
  • To assess the relationship between DS and all-cause mortality risk in HF patients.

Main Methods:

  • A prospective study involving 130 adult outpatients with HF.
  • Depressive symptoms screened using the Beck Depression Inventory Scale-second edition (BDI-II).
  • All-cause mortality and CV hospitalizations tracked over 6 years; logistic regression used for analysis.

Main Results:

  • 44% of HF patients exhibited depressive symptoms.
  • DS independently predicted all-cause mortality (OR: 2.905) and CV hospitalizations (OR: 3.169).
  • These associations remained significant after adjusting for clinical risk factors.

Conclusions:

  • Depressive symptoms are independent predictors of mortality and CV hospitalizations in HF patients.
  • The impact of DS on outcomes in HF persists over a 6-year period.
  • This is the first study in a Portuguese population to demonstrate these findings.
Abstract

Keywords:
DepressionHeart failureHospitalizationsMortalityPrognosis

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