Related Experiment Video
Updated: Mar 20, 2026

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
Published on: January 10, 2025
A Conceptual Overview and Commentary on Gender Dysphoria
1Dr. Berlin is Associate Professor, Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Director, The Johns Hopkins Sexual Behaviors Consultation Unit, and Director, National Institute for the Study, Prevention and Treatment of Sexual Trauma, Baltimore, MD. fredsberlinmd@comcast.net.
Abstract:
Gender Dysphoria is a distressed state of mind that is of interest to psychiatrists, including forensic psychiatrists. Forensic matters can be best addressed only after one has a good appreciation of relevant psychiatric knowledge and concepts. In this commentary I review the nature of Gender Dysphoria, its relationship to cross-dressing and erotic arousal, and the question of whether it should be thought of as a psychiatric disorder. I also review the complexity of sex and gender; alternative conceptualizations of Gender Dysphoria, its etiology, its multicultural history, and its typical course over time in a given individual. Finally, I summarize treatment options, treatment outcomes, and difficulties of treating Gender Dysphoria within an inmate population.
Related Concept Videos
Socioemotional Experience and Gender Development
Psychosexual Stages of Personality: Phallic
Panic Disorder
Dissociative Identity Disorder
Self-Discrepancy and Its Effects
Stereotype Content Model

