Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Novel CNNM2 variant causing hypomagnesemia and early-onset calcium pyrophosphate deposition disease: A case report.

Joint bone spine·2025
Same author

Real-world efficacy and safety of burosumab in tumor-induced osteomalacia: case series from an early access program.

JBMR plus·2025
Same author

Identifying a predictive level of serum C-terminal telopeptide associated with a low risk of medication-related osteonecrosis of the jaw secondary to oral surgery: A systematic review and meta-analysis.

PloS one·2025
Same author

The T-cell response to SARS-CoV- 2 vaccination persists beyond six months in rheumatoid arthritis patients treated with rituximab.

Arthritis research & therapy·2025
Same author

NSAID: Current limits to prescription.

Joint bone spine·2023
Same author

Anti-Jo-1 autoantibodies: biomarkers of severity and evolution of the disease in antisynthetase syndrome.

Arthritis research & therapy·2023

Related Experiment Video

Updated: Mar 20, 2026

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
10:25

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping

Published on: September 25, 2019

49.6K

Bone infarcts: Unsuspected gray areas?

Pierre Lafforgue1, Sophie Trijau2

  • 1Aix-Marseille université, faculté de médecine, 27, boulevard Jean-Moulin, 13005 Marseille, France; Service de rhumatologie, hôpital Sainte-Marguerite, 270, boulevard de Sainte-Marguerite, 13009 Marseille, France.

Joint Bone Spine
|May 30, 2016
PubMed
Summary
This summary is machine-generated.

Bone infarcts, or avascular necrosis (AVN) of bone, are common but poorly understood. While often asymptomatic, they can indicate systemic AVN requiring further investigation.

Keywords:
Avascular necrosisBone infarctionOsteonecrosis

More Related Videos

Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG
10:31

Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG

Published on: December 28, 2014

14.5K
Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery
08:14

Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery

Published on: July 31, 2014

38.8K

Related Experiment Videos

Last Updated: Mar 20, 2026

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
10:25

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping

Published on: September 25, 2019

49.6K
Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG
10:31

Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG

Published on: December 28, 2014

14.5K
Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery
08:14

Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery

Published on: July 31, 2014

38.8K

Area of Science:

  • Radiology
  • Orthopedic Surgery
  • Pathology

Background:

  • Bone infarcts, avascular necrosis (AVN) in long bone metaphyses/diaphyses, are distinct from epiphyseal AVN/osteonecrosis.
  • Despite commonality, scientific evidence on bone infarcts is notably scarce, with unknown prevalence.
  • Typical sites include distal femur and tibia; diaphyseal or upper limb involvement is rare without specific conditions.

Purpose of the Study:

  • To review the current understanding and diagnostic features of bone infarcts.
  • To highlight the clinical presentation and imaging characteristics of bone infarcts.
  • To emphasize the significance of bone infarcts as potential markers for systemic avascular necrosis.

Main Methods:

  • Review of existing scientific literature on bone infarcts.
  • Analysis of radiographic and magnetic resonance imaging (MRI) findings.
  • Correlation of bone infarcts with systemic conditions and epiphyseal AVN.

Main Results:

  • Bone infarcts occur in half of symptomatic cases, often initially silent on standard radiographs.
  • Radiographs may show high-density lesions or periosteal reactions; MRI provides consistent diagnostic features.
  • Multifocal bone infarcts are common (over 50%) and frequently associated with epiphyseal AVN.

Conclusions:

  • Bone infarcts generally have a good prognosis but can signal broader systemic AVN.
  • Patients with bone infarcts require investigation for risk factors and other AVN foci.
  • Early detection and evaluation are crucial, as associated AVN may threaten function.