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Cerebellar cortical infarct cavities and vertebral artery disease

Laurens J L De Cocker1,2, A Compter3, L J Kappelle3

  • 1Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands. laurens_de_cocker@hotmail.com.

Neuroradiology
|May 30, 2016
PubMed

Insights

Cerebellar cortical infarct cavities are common in patients with symptomatic vertebral artery stenosis, often appearing without prior stroke history. These findings suggest they should be recognized as incidental brain infarcts on MRI.

Area of Science:

  • Neurology
  • Neuroradiology
  • Cerebrovascular Disease

Background:

  • Cerebellar cortical infarct cavities are a newly recognized finding.
  • They are associated with atherothromboembolic cerebrovascular disease and impaired physical function.
  • Their relationship with symptomatic vertebrobasilar ischemia and vascular risk factors requires investigation.

Purpose of the Study:

  • To investigate the association between cerebellar cortical infarct cavities and symptomatic vertebrobasilar ischemia.
  • To explore the relationship of these cavities with common vascular risk factors.

Main Methods:

  • MR images of 46 patients with recent vertebrobasilar TIA or stroke and significant vertebral artery stenosis were evaluated.
  • Data on demographics and vascular risk factors were collected.
  • Poisson regression analyses were used to calculate adjusted risk ratios.

Main Results:

  • Cerebellar cortical infarct cavities were present in 35% of patients.
  • Only one patient with cavities had a known prior vertebrobasilar TIA or stroke.
  • Risk factor profiles did not differ between patients with and without cavities.

Conclusions:

  • Cerebellar cortical infarct cavities are observed in one-third of patients with symptomatic vertebral artery stenosis.
  • These cavities often occur in patients without a prior history of vertebrobasilar events.
  • They should be considered common incidental brain infarcts on routine MRI.
Abstract

Keywords:
CerebellumCortical infarct cavityIncidental brain infarctionIschaemiaMRI

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