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Transient hair loss during treatment with dimethyl-fumarate for multiple sclerosis
Francesco Antonio Losavio1, Matteo Lucchini1, Chiara De Fino1
1Institute of Neurology, Department of Geriatrics, Neurosciences and Orthopedics, Catholic University, Largo A. Gemelli 8, Rome, Italy.
Introduction:
Dimethyl-fumarate is a recently approved drug for relapsing-remitting Multiple Sclerosis in Italy.
Clinical Case:
A 55-year-old woman started therapy with dimethyl-fumarate on June 2014; it was well-tolerated aside from moderate flushing. Starting September 2014 she noticed a progressive hair loss, that neither the dermatological examination nor clinical and medical history nor blood investigations could explain. The hair loss slowed down after two months and was followed by a hair growth back.
Discussion:
Transient hair loss is not a reported side effect of dimethyl-fumarate therapy but by excluding any known cause we attributed it to the beginning of the new therapy.
