Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fundamentals of Nursing Process II01:25

Fundamentals of Nursing Process II

6.0K
There are several characteristics related to delivering nursing care. One vital characteristic of the nursing process is that it can be used to protect nurses and justify the provided care. Productive use of the nursing process requires the knowledge and skills of nurses to assess and solve issues. Nurses should develop and strengthen their critical thinking skills and evidence-based nursing interventions to improve their skills in formulating nursing care plans. A well-defined approach to...
6.0K
Fundamentals of Nursing Process I01:27

Fundamentals of Nursing Process I

9.4K
The nursing process is the core of practice for every registered nurse to deliver holistic, patient-focused care. The following are the five steps in the nursing process.
9.4K
The Scientific Method in Nursing Process01:18

The Scientific Method in Nursing Process

19.2K
The scientific method provides the foundation for any research. It is the most reliable and objective of all forms of gaining knowledge and guides in applying research-based evidence in practice and conducting future research.
When using research findings to change practice, one must understand the process used to guide a study. The scientific method is a systematic, step-by-step process that supports the data's validity, reliability, and generalizability. As a result, findings can be...
19.2K
Methods of Documentation V: CBE01:23

Methods of Documentation V: CBE

1.5K
Charting by Exception, or CBE, is a method of documentation used in healthcare, particularly in nursing, that focuses on documenting only significant or abnormal findings rather than recording every detail. This approach aims to streamline the documentation process, improve efficiency, and ensure that healthcare providers can quickly identify deviations from normalcy in patient assessments.
In CBE, healthcare professionals establish predefined standards of practice that define what constitutes...
1.5K
Handwashing III: During the Procedure and Post-Procedure Steps01:15

Handwashing III: During the Procedure and Post-Procedure Steps

3.2K
To wash hands properly, follow these steps:
3.2K
Fixation and Sectioning01:03

Fixation and Sectioning

8.8K
Two basic types of preparation are used to visualize specimens with a light microscope: wet mounts and fixed specimens.
The simplest type of preparation is the wet mount, in which the specimen is placed in a drop of liquid on the slide. A liquid specimen can be directly deposited on the slide using a dropper. Solid specimens, such as skin scraping, can be placed on the slide before adding a drop of liquid to prepare the wet mount. Sometimes the liquid is simply water, but stains are often added...
8.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Case Report: When genetic diagnosis comes late: lessons from a DEND syndrome patient successfully transitioned to sulfonylurea.

Frontiers in clinical diabetes and healthcare·2025
Same author

New Perspectives on the Use of Resveratrol in the Treatment of Metabolic and Estrogen-Dependent Conditions Through Hormonal Modulation and Anti-Inflammatory Effects.

Current issues in molecular biology·2025
Same author

<i>FTO</i> rs17817449 Variant Increases the Risk of Severe Obesity in a Brazilian Cohort: A Case-Control Study.

Diabetes, metabolic syndrome and obesity : targets and therapy·2025
Same author

Genomic deletions on 16p11.2 associated with severe obesity in Brazil.

Frontiers in endocrinology·2025
Same author

Guidance and Position of RINN22 regarding Precision Nutrition and Nutriomics.

Lifestyle genomics·2024
Same author

Effect of Genotype on the Response to Diet in Cardiovascular Disease-A Scoping Review.

Healthcare (Basel, Switzerland)·2024

Related Experiment Videos

[In Process Citation].

Márcia Fófano do Lago1, Vanessa Chaia Kaippert, Débora Lopes Souto

  • 1Department of Nutrition and Dietetics and Nutrition Evaluation Laboratory. Federal University of Rio de Janeiro. Institute of Nutrition Josué de Castro. Rio de Janeiro, Brazil. marcia@correo.com.

Nutricion Hospitalaria
|May 31, 2016
PubMed
Summary
This summary is machine-generated.

Dietary monounsaturated fatty acids (MUFAs) improved insulin resistance in obese women with the PPARγ2 Pro12Pro genotype. Polyunsaturated fatty acids (PUFAs) showed a modest effect on body mass index, but MUFAs were more effective for metabolic improvements.

Related Experiment Videos

Area of Science:

  • Nutritional Science
  • Genetics
  • Metabolic Health

Background:

  • Dietary fatty acid type influences obesity and its complications, modulated by gene polymorphisms like PPARγ2.
  • The specific effects of lipid unsaturation on lipid and glucose metabolism, and weight loss, remain unclear.
  • The PPARγ2 gene, specifically the Pro12Pro genotype, may influence individual responses to dietary fats.

Purpose of the Study:

  • To evaluate the impact of diets rich in polyunsaturated fatty acids (PUFAs) versus monounsaturated fatty acids (MUFAs) on anthropometric and biochemical variables.
  • To assess the influence of these diets on body weight, glycemic profile, and lipid profile in obese women with the PPARγ2 Pro12Pro genotype.
  • To determine differential effects of PUFAs and MUFAs on metabolic health markers in a specific genetic context.

Main Methods:

  • Eighteen obese women with the Pro12Pro genotype were randomly assigned to either a PUFA-rich diet (n=8) or a MUFA-rich diet (n=10).
  • Anthropometric (BMI, waist circumference) and biochemical (glucose, insulin, HOMA-IR, lipid profile) variables were measured before and after a 45-day intervention.
  • Statistical analysis compared changes in variables between the two dietary groups.

Main Results:

  • No significant differences in anthropometric and biochemical variables were observed between groups pre- or post-intervention (p > 0.05).
  • Body Mass Index (BMI) decreased in the PUFA group (p = 0.01), potentially due to lower overall lipid content.
  • The MUFA diet led to significant reductions in glucose (p = 0.03), insulin (p = 0.03), and HOMA-IR (p = 0.02), indicating improved insulin sensitivity.

Conclusions:

  • Monounsaturated fatty acids (MUFAs) demonstrated greater efficacy in reducing insulin resistance among obese women with the PPARγ2 Pro12Pro genotype.
  • Despite high total lipid and saturated fatty acid intake, MUFAs provided metabolic benefits.
  • Dietary fat quality, specifically MUFA content, plays a crucial role in managing insulin resistance in genetically predisposed individuals.