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Strain Pattern on Electrocardiogram Is Associated with Increased Carotid Intima-Media Thickness in Patients with

Meliza Goi Roscani1, Gustavo N Augusto2, Tainá F C Valadão2

  • 1Medicine Department, Cardiology Division, São Carlos Federal University -UFSCar, São Carlos, Brazil.

Annals of Vascular Surgery
|May 31, 2016
PubMed

Insights

The electrocardiogram (EKG) strain pattern in patients with aortic stenosis (AS) is a significant indicator of atherosclerosis. This finding suggests further investigation for subclinical atherosclerotic disease in these patients.

Area of Science:

  • Cardiology
  • Vascular Biology
  • Diagnostic Imaging

Background:

  • Aortic stenosis (AS) frequently coexists with coronary artery disease, sharing pathological mechanisms with atherosclerosis.
  • Electrocardiogram (EKG) strain pattern, a marker for AS severity, reflects myocardial changes and ischemia.
  • The study investigates the potential of EKG strain pattern as a marker for atherosclerosis in AS patients.

Purpose of the Study:

  • To determine if an EKG strain pattern is associated with atherosclerosis in patients with moderate to severe AS.
  • To correlate the presence of EKG strain pattern with carotid intima-media thickness (CIMT).

Main Methods:

  • Fifty-two patients with moderate or severe AS were evaluated.
  • Methods included clinical assessment, EKG, transthoracic echocardiography, and carotid ultrasonography.
  • Statistical analysis was performed to assess associations.

Main Results:

  • A significant association was found between left ventricular EKG strain and increased CIMT (P=0.001).
  • The presence of EKG strain increased the odds of abnormal CIMT (P=0.004, OR 9.7).
  • EKG strain was also linked to the presence of atherosclerotic plaque in carotid arteries (P=0.011).

Conclusions:

  • The EKG strain pattern in AS patients is a significant marker for atherosclerosis.
  • Patients with AS and EKG strain pattern warrant further evaluation for subclinical atherosclerotic disease.
Abstract

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