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Updated: Mar 20, 2026

Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells
Published on: May 20, 2020
Pulmonary Tumor Thrombotic Microangiopathy: A New Paraneoplastic Syndrome?
Corey A Carter1, Jan J Scicinski2, Harry E Lybeck3
1Murtha Cancer Center, Walter Reed National Military Medical Center, Bethesda, Md., USA.
Abstract:
This report, based on data from a clinical case, proposes that pulmonary tumor thrombotic microangiopathy, an underdiagnosed cause of pulmonary hypertension and death in patients with adenocarcinoma, is a paraneoplastic syndrome (PNS). Clinicians in general must be alert to the presence or development of PNS that may precede, coincide with, follow, or herald the recurrence or the primary diagnosis of malignancy since early recognition facilitates prompt diagnosis and treatment.
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