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Updated: Mar 20, 2026

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness
Published on: March 18, 2022
[Microcrystalline stress in the pathogenesis of osteoarthritis]
A I Dubikov1, M A Kabalyk1, T Yu Koretskaya1
1Pacific State Medical University, Ministry of Health of Russia, Vladivostok, Russia.
Aim:
To estimate the rate of articular cartilage microcrystallization in osteoarthritis (OA).
Subjects And Methods:
The investigation included 110 people who had undergone total endoprosthetic replacement for coxarthrosis. A total of 50 patients with total hip endoprosthetic replacement for femoral neck fractures were recruited as a comparison group. An X-ray diffractometer was used to detect crystals.
Results:
Cartilage mineralization was seen in 72% of the patients with late-stage OA.
Conclusion:
Articular cartilage microcrystalline stress is a constant sign of late-stage OA requiring further clinical interpretation.
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