Chronic obstructive pulmonary disease and HIV: are we appropriately screening?
Bahareh Ghadaki1, Nadine Kronfli2, Thuva Vanniyasingam3
1a Department of Infectious Disease and Medical Microbiology , Michael G. DeGroote School of Medicine, McMaster University , Hamilton , Ontario , Canada.
Smoking significantly increases respiratory symptoms and diseases like COPD in people with HIV. Many symptomatic smokers meet screening criteria but lack a diagnosis, indicating under-recognition of COPD.
Area of Science:
- Pulmonology
- Infectious Diseases
- Public Health
Background:
- Individuals with human immunodeficiency virus (HIV) have an elevated risk for chronic obstructive pulmonary disease (COPD).
- Smoking is a primary risk factor for COPD and other respiratory ailments.
- Understanding the impact of smoking on respiratory health in the HIV population is crucial for patient care.
Purpose of the Study:
- To investigate the effects of smoking on respiratory symptoms and diseases among HIV-positive individuals.
- To assess the adequacy of COPD screening in symptomatic HIV-positive patients based on Canadian Thoracic Society (CTS) guidelines.
Main Methods:
- A self-administered questionnaire was used to collect data from 247 HIV-positive participants.
- Respiratory symptoms and diseases were analyzed, with effects of smoking reported as odds ratios (ORs).
- COPD screening criteria were adapted from the CTS guidelines.
Main Results:
- Smoking was significantly associated with increased odds of respiratory symptoms: wheeze (OR 4.8), phlegm (OR 4.9), cough (OR 7.0), and dyspnea (OR 7.2).
- Smoking increased the odds of respiratory diseases, including COPD (OR 4.9) and bronchitis (OR 3.8).
- Among HIV-positive smokers, 40% met CTS COPD screening criteria, yet only 12% reported a COPD diagnosis, highlighting a diagnostic gap.
Conclusions:
- Smoking poses a substantial burden on the respiratory health of the HIV-positive population.
- HIV-positive smokers experience significantly higher rates of respiratory symptoms and diseases compared to non-smokers.
- There is a concerning under-recognition and under-diagnosis of COPD among HIV-positive smokers who meet screening criteria.
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