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Analysis of measles-related hospitalizations in Tuscany from 2000 to 2014
E Berti1, S Sollai1, E Orlandini2
1Anna Meyer Children's University Hospital,Department of Health Sciences,University of Florence,Florence,Italy.
Insights
Measles hospitalization rates increased in Tuscany, Italy, from 2000-2014, particularly in young adults, despite elimination efforts. Infants under one year old had the highest rates, with pneumonia as the main complication.
Area of Science:
- Epidemiology
- Public Health
- Infectious Diseases
Background:
- Measles elimination efforts have been ongoing in Tuscany, Italy.
- Hospitalization data provides insights into measles incidence and trends.
Purpose of the Study:
- To evaluate measles incidence and hospitalization rate changes in children and adults in Tuscany over a 14-year period (2000-2014).
- To identify changes in measles susceptibility within different age groups.
Main Methods:
- Analysis of regional hospital discharge database data.
- Inclusion of pediatric and adult cases of measles.
- Stratification of data by age group.
Main Results:
- Overall measles hospitalization rates increased from 0.45 to 0.85 per 100,000 population.
- Significant increase in hospitalization rates observed in young adults.
- Infants under one year old had the highest hospitalization rate.
- Pneumonia was the most common complication; no deaths were reported.
Conclusions:
- Measles remains a public health concern in Tuscany, characterized by periodic outbreaks.
- Increased measles susceptibility in young adults necessitates targeted public health strategies.
- Focus on vulnerable groups like infants and young adults is crucial for future measles control.
Abstract:
To evaluate measles incidence and its relevant changes over a 14-year period (2000-2014), we analysed data from the regional hospital discharge database on children and adults hospitalized in Tuscany, Italy. A total of 181 paediatric and 413 adult cases were identified. Despite all the efforts towards regional measles elimination, we observed that the overall measles hospitalization rates for children and adults living in Tuscany globally increased from 0·45 to 0·85/100 000 during the study period (P = 0·001) showing fluctuations due to periodic measles outbreaks. Data stratified by age group showed that the hospitalization rate significantly increased in young adults over the study period, confirming an increase in susceptibility to measles in this subpopulation. Conversely, no statistically significant difference was observed in the hospitalization rate in the other age groups. However, children aged <1 year still exhibit the highest hospitalization rate. Pneumonia represented the most common complication in both the adult and children subsets. No death was reported. Measles still represents a public health problem, and national strategies should be implemented, focusing on emergent susceptible subsets, such as infants and young adults.
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