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Demographic and clinical characteristics and risk factors for Staphylococcal scalded skin syndrome in Hunan
Juan Su1, Ji Li1, Haiyan Luo2
1Department of Dermatology, Xiangya Hospital, Central South University, Changsha 410008; Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, Changsha 410008, China.
Insights
Staphylococcal scalded skin syndrome (SSSS) primarily affects young children and can involve multiple organs. Early diagnosis and prompt antimicrobial treatment are crucial for successful recovery from SSSS.
Area of Science:
- Pediatrics
- Dermatology
- Infectious Diseases
Background:
- Staphylococcal scalded skin syndrome (SSSS) is a serious skin condition.
- Understanding its risk factors and clinical presentation is vital for effective management.
Purpose of the Study:
- To identify risk factors, clinical features, and treatment outcomes for SSSS.
- To analyze data from a large cohort of pediatric patients.
Main Methods:
- Retrospective analysis of 290 patients diagnosed with SSSS.
- Review of clinical features, laboratory findings, and treatment protocols.
Main Results:
- 76.6% of patients were under 3 years old.
- Common findings included fever (168 patients) and elevated white blood cell count (177 patients).
- Staphylococci were identified in 119 positive bacterial cultures; all patients recovered with antimicrobial therapy.
Conclusions:
- SSSS predominantly affects infants and children under 3.
- The condition can present with multi-organ symptoms.
- Early diagnosis and prompt antimicrobial treatment are key to successful outcomes.
Objective:
To realize the risk factors, clinical features, and treatments of Staphylococcal scalded skin syndrome (SSSS).
Methods:
The clinical features, laboratory findings, and treatment were retrospectively analyzed in 290 patients from Hunan Children's Hospital.
Results:
Of the 290 patients, less than 3 years old children were 76.6%. One hundred and nine patients had induced factors, and 177 patients had elevated white blood cell count. There were 168 patients with SSSS accompanied with fever, 34 patients accompanied with diarrhea, and 58 patients associated with septicemia. Eighty-five patients performed the bacterial cultures of the skin secretions, 21 did the throat swab, and 13 did both of the skin secretions and throat swab. Bacterial culture results showed that 119 samples were positive for Staphylococci. All patients were cured after antimicrobial therapy. The skin lesions were improved in 3.26 d. The mean hospital stay was 6.55 d. Recovery time of the body temperature was 3.48 d in average.
Conclusion:
SSSS predominates in infants and children under 3 years old, and has tendency to combine with multi-organ symptoms. The early diagnosis and active antimicrobial treatment are the keys of successful treatments.
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