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Related Concept Videos

Obesity01:24

Obesity

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The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
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Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
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Drug Dosing: Obese Patients01:21

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In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
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Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
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Related Experiment Video

Updated: Mar 20, 2026

Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice
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Bariatric Surgery in Youth.

Tamar L Mirensky1

  • 1Division of Pediatric General and Thoracic Surgery, Department of Surgery, The Mount Sinai Hospital, 5 East 98th Street, 10th Floor, Box 1259, New York, NY 10029-6574, USA.

Endocrinology and Metabolism Clinics of North America
|June 1, 2016
PubMed
Summary

Bariatric surgery is an effective weight management solution for obese youth, showing excellent short-term results. Long-term data are pending, but current outcomes show great promise for this population.

Keywords:
Adolescent obesityBariatric surgeryChildhood obesityGastric bypassObesitySleeve gastrectomy

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Area of Science:

  • Pediatric Endocrinology
  • Surgical Innovation
  • Obesity Medicine

Background:

  • Obesity in youth is a growing public health concern.
  • Bariatric surgery is increasingly considered for managing severe pediatric obesity.
  • Established benefits exist for adult bariatric surgery patients.

Purpose of the Study:

  • To evaluate the efficacy and safety of bariatric surgery in obese youth.
  • To assess short- and intermediate-term outcomes following bariatric procedures in adolescents.
  • To explore the potential of bariatric surgery for long-term obesity management in young individuals.

Main Methods:

  • Review of current literature on bariatric surgery in pediatric populations.
  • Analysis of short- and intermediate-term outcomes from published studies.
  • Assessment of comorbidity management and weight reduction efficacy.

Main Results:

  • Bariatric surgery demonstrates significant and sustained weight reduction in selected obese youth.
  • Associated comorbidities show marked improvement post-surgery.
  • Excellent short- and intermediate-term outcomes have been reported, with a favorable safety profile.

Conclusions:

  • Bariatric surgery is a clinically effective and cost-effective option for sustained weight management in obese youth.
  • While long-term data are still being gathered, current evidence suggests bariatric surgery holds significant promise for this population.
  • Careful patient selection is crucial for optimizing outcomes in pediatric bariatric surgery.