Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pleural Effusion II: Symptoms and Management01:28

Pleural Effusion II: Symptoms and Management

1000
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
1000
Pleural Effusion I: Introduction01:25

Pleural Effusion I: Introduction

5.3K
Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
5.3K
Pneumothorax-II01:27

Pneumothorax-II

1.4K
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
1.4K
Pleural Disorders: Types and Brief Description01:30

Pleural Disorders: Types and Brief Description

893
The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
893
Pleura of the Lungs01:13

Pleura of the Lungs

9.4K
The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
9.4K
Endoscopic Studies II: Thoracocentesis01:26

Endoscopic Studies II: Thoracocentesis

1.9K
Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
1.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Targeting KRAS for cancer therapy.

British journal of pharmacology·2026
Same author

Prognostic Value of Lung Injury Biomarkers in Patients Hospitalized With COVID-19 Without Respiratory Failure at Admission.

Critical care medicine·2026
Same author

A Massive Cavernous Mediastinal Haemangioma Causing Superior Vena Cava Obstruction and Extending to the Supraclavicular Space: A Case Report.

Cureus·2026
Same author

PA200 differentially regulates the proteasome and inhibits migration of NSCLC cells.

Journal of cell science·2026
Same author

Remdesivir: Real-World Effectiveness and Safety in Individuals Hospitalized for Non-COVID Reasons and Non-Hospitalized High-Risk Patients During the Omicron Era in Greece.

Microorganisms·2026
Same author

Comparative analysis of malignant pleural effusion and peripheral blood reveals unique T cell signatures associated with survival in mesothelioma patients.

Oxford open immunology·2026
Same journal

Implementing acute exacerbations of COPD care bundles: evidence, effectiveness and future directions.

European respiratory review : an official journal of the European Respiratory Society·2026
Same journal

Preclinical human models of primary ciliary dyskinesia.

European respiratory review : an official journal of the European Respiratory Society·2026
Same journal

Bench evidence, bedside uncertainty: hyperoxia, mechanical ventilation and lung injury.

European respiratory review : an official journal of the European Respiratory Society·2026
Same journal

Respiratory support in paediatric patients with bronchiolitis: a systematic review and meta-analysis.

European respiratory review : an official journal of the European Respiratory Society·2026
Same journal

Air pollution-induced airway epithelial barrier dysfunction in COPD: a narrative review of mechanisms and therapeutic implications.

European respiratory review : an official journal of the European Respiratory Society·2026
Same journal

Utilising human cellular models of primary ciliary dyskinesia: a scoping review.

European respiratory review : an official journal of the European Respiratory Society·2026
See all related articles

Related Experiment Video

Updated: Mar 20, 2026

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
03:22

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion

Published on: November 10, 2023

1.8K

Malignant pleural effusion: from bench to bedside.

Ioannis Psallidas1, Ioannis Kalomenidis2, Jose M Porcel3

  • 1Oxford Respiratory Trials Unit, Oxford Centre for Respiratory Medicine, Oxford University Hospitals Trust, Oxford, UK ioannis.psallidas@ndm.ox.ac.uk.

European Respiratory Review : an Official Journal of the European Respiratory Society
|June 2, 2016
PubMed
Summary
This summary is machine-generated.

Malignant pleural effusion (MPE) management has advanced, improving patient care from palliative to ambulatory treatments. This overview covers recent MPE diagnostics, pathophysiology, and future research directions.

More Related Videos

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
08:01

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

Published on: April 21, 2022

2.3K
Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
07:54

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice

Published on: December 21, 2019

7.4K

Related Experiment Videos

Last Updated: Mar 20, 2026

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
03:22

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion

Published on: November 10, 2023

1.8K
Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
08:01

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

Published on: April 21, 2022

2.3K
Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
07:54

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice

Published on: December 21, 2019

7.4K

Area of Science:

  • Oncology
  • Pulmonology
  • Thoracic Medicine

Background:

  • Malignant pleural effusion (MPE) is a serious condition impacting quality of life, morbidity, and mortality.
  • Rising incidence and healthcare costs associated with MPE necessitate improved management strategies.
  • Current MPE management is primarily palliative, with limited median survival (3-12 months).

Purpose of the Study:

  • To provide a comprehensive overview of current advances in malignant pleural effusion (MPE) research and clinical practice.
  • To highlight recent progress in MPE pathophysiology, diagnostics, imaging, and treatment.
  • To identify unanswered questions and suggest future research directions in the MPE field.

Main Methods:

  • Review of recent literature on malignant pleural effusion (MPE).
  • Synthesis of current knowledge on MPE pathophysiology, diagnostics, and management.
  • Identification of emerging trends and future research needs in MPE.

Main Results:

  • Significant progress has been made in understanding MPE pathophysiology, diagnostics, and management over the last decade.
  • Patient treatment has shifted towards ambulatory care, with advancements in genotyping and phenotyping.
  • Formerly bed-ridden patients can now be managed on an outpatient basis.

Conclusions:

  • Advances in MPE research have led to improved diagnostic and therapeutic approaches.
  • Future research should focus on addressing current clinical practice gaps and further optimizing MPE management.
  • The field is moving towards more personalized and less invasive treatments for malignant pleural effusion.