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Published on: May 19, 2020
Anterior mitral valve aneurysm: a rare sequelae of aortic valve endocarditis
Rajesh Janardhanan1, Muhammad Umar Kamal2, Irbaz Bin Riaz2
1Department of Cardiology, Sarver Heart Center, Banner University Medical Center, Tucson, Arizona, USA raj@shc.arizona.edu.
Unlabelled:
SummaryIn intravenous drug abusers, infective endocarditis usually involves right-sided valves, with Staphylococcus aureus being the most common etiologic agent. We present a patient who is an intravenous drug abuser with left-sided (aortic valve) endocarditis caused by Enterococcus faecalis who subsequently developed an anterior mitral valve aneurysm, which is an exceedingly rare complication. A systematic literature search was conducted which identified only five reported cases in the literature of mitral valve aneurysmal rupture in the setting of E. faecalis endocarditis. Real-time 3D-transesophageal echocardiography was critical in making an accurate diagnosis leading to timely intervention.
Learning Objectives:
Early recognition of a mitral valve aneurysm (MVA) is important because it may rupture and produce catastrophic mitral regurgitation (MR) in an already seriously ill patient requiring emergency surgery, or it may be overlooked at the time of aortic valve replacement (AVR).Real-time 3D-transesophageal echocardiography (RT-3DTEE) is much more advanced and accurate than transthoracic echocardiography for the diagnosis and management of MVA.
Insights
Infective endocarditis in intravenous drug users can affect the left side of the heart, leading to rare mitral valve aneurysms. Early diagnosis with real-time 3D-transesophageal echocardiography is crucial for managing this complication.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Imaging
Background:
- Infective endocarditis (IE) in intravenous drug abusers (IDUs) typically affects right-sided valves, with Staphylococcus aureus as the common pathogen.
- Left-sided IE in IDUs is less common but can lead to severe complications.
Observation:
- A case of left-sided IE caused by Enterococcus faecalis in an IDU is presented.
- The patient developed an anterior mitral valve aneurysm, an exceptionally rare complication of IE.
- A literature review identified only five prior cases of mitral valve aneurysmal rupture associated with E. faecalis endocarditis.
Findings:
- Real-time 3D-transesophageal echocardiography (RT-3DTEE) proved critical for accurate diagnosis of the mitral valve aneurysm.
- Mitral valve aneurysms (MVAs) pose a risk of rupture, leading to severe mitral regurgitation (MR) and requiring emergency surgery.
- MVAs may be overlooked during aortic valve replacement (AVR) if not accurately diagnosed.
Implications:
- Early recognition and diagnosis of MVAs are vital for timely intervention in critically ill patients.
- RT-3DTEE offers superior accuracy for MVA diagnosis and management compared to traditional echocardiography.
- This case highlights the importance of considering left-sided IE and its rare complications in IDUs.
Related Concept Videos
Mitral Stenosis I: Introduction
Mitral Regurgitation I: Introduction
Mitral Valve Prolapse I: Introduction
Aortic Regurgitation I: Introduction
Mitral Stenosis III: Medical Management
Aortic Regurgitation II: Clinical Features and Diagnostic Tests

