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[THE EXPERTS CONSENSUS FOR ANTICOAGULANT THERAPY OF VENOUS THROMBOEMBOLISM IN 2016 YR. SIGNIFICANCE OF THE RIVAROXABAN INVESTIGATIONS PROGRAM FOR CHANGES OF APPROACHES, CONCERNING TREATMENT OF THE DEEP VEINS THROMBOSIS AND PULMONARY THROMBOEMBOLISM].

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[HEMOSTASIOLOGIC INDICES AFTER LAPAROSCOPIC CHOLECYSTECTOMY FOR AN ACUTE CHOLECYSTITIS].

I M Gudz, O O Tkachuk-Grygorchuk, O L Tkachuk

    Klinichna Khirurhiia
    |June 3, 2016
    PubMed
    Summary

    Acute cholecystitis patients show hypercoagulation pre-surgery. Laparoscopic surgery can accelerate blood clotting, limiting medicinal thromboprophylaxis due to hemorrhage risk.

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    Area of Science:

    • Investigates hematological parameters in surgical pathology.
    • Focuses on coagulation and hemostasis in acute cholecystitis.

    Context:

    • Acute cholecystitis is an inflammatory condition of the gallbladder.
    • Coagulation status is crucial for surgical risk assessment and management.

    Purpose:

    • To evaluate coagulometry and thromboelastography (THEG) indices in acute cholecystitis patients.
    • To assess changes in coagulation following laparoscopic cholecystectomy.

    Summary:

    • Preoperative assessment revealed hypercoagulation tendencies in patients with acute cholecystitis, increasing with disease severity.
    • Post-laparoscopic cholecystectomy, particularly after severe operations, accelerated blood clotting kinetics were observed via THEG.
    • These findings indicate a heightened risk of hemorrhage, restricting the use of medicinal thromboprophylaxis.

    Impact:

    • Highlights the dynamic changes in coagulation associated with acute cholecystitis and its surgical management.
    • Informs clinical decisions regarding thromboprophylaxis in patients undergoing cholecystectomy.
    • Emphasizes the importance of monitoring coagulation status in surgical patients with inflammatory conditions.