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Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth
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Editorial: A New Spin on Magnetic Resonance Elastography.

Rekha Kishore1, Rohit Loomba2, Richard K Sterling3

  • 1Department of Radiology, Virginia Commonwealth University Health System, Richmond, Virginia, USA.

The American Journal of Gastroenterology
|June 3, 2016
PubMed
Summary

Magnetic resonance elastography (MRE) can identify liver fibrosis. Three-dimensional MRE (3D-SE-EPI MRE) offers advantages over two-dimensional MRE (2D-GRE MRE) in speed, volume, and reliability, potentially becoming the new standard.

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Area of Science:

  • Hepatology
  • Medical Imaging
  • Biophysics

Background:

  • Hepatic fibrosis is a critical indicator of liver disease progression.
  • Accurate identification of fibrosis, from early stages to cirrhosis, remains a significant clinical challenge.
  • Liver elastography, measuring tissue stiffness, is a promising imaging technique for fibrosis assessment.

Purpose of the Study:

  • To compare the efficacy of two-dimensional (2D) gradient-recalled echo magnetic resonance elastography (MRE) with three-dimensional (3D) spin-echo echo-planar imaging MRE.
  • To evaluate the performance of these MRE techniques in assessing liver fibrosis.

Main Methods:

  • Utilized two-dimensional gradient-recalled echo magnetic resonance elastography (2D-GRE MRE).
  • Employed three-dimensional spin-echo echo-planar imaging MRE (3D-SE-EPI MRE).
  • Compared imaging volume, acquisition time, and technical failure rates between the two MRE methods.

Main Results:

  • 3D-SE-EPI MRE successfully imaged a larger liver volume compared to 2D-GRE MRE.
  • The 3D-SE-EPI MRE technique required less time for image acquisition.
  • Fewer technical failures were observed with the 3D-SE-EPI MRE method.

Conclusions:

  • 3D-SE-EPI MRE demonstrates superior performance over 2D-GRE MRE for liver fibrosis assessment.
  • The enhanced efficiency and reliability of 3D-SE-EPI MRE suggest its potential to become the new gold standard in liver elastography.