Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genomics02:02

Genomics

41.6K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
41.6K
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

823
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
823
Synthetic Biology02:55

Synthetic Biology

5.8K
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
5.8K
Genome Annotation and Assembly03:36

Genome Annotation and Assembly

21.4K
The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
21.4K
Human Genetics01:28

Human Genetics

1.8K
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
1.8K
Organization of Genes02:07

Organization of Genes

74.2K
Overview
74.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Distinct Hippocampal Cellular Pathologies Influence Cognition Across Diagnostic Categories, Also Distinguishing Schizophrenia from Affective Psychoses.

bioRxiv : the preprint server for biology·2026
Same author

The Future of <i>DSM</i>: Response to Letters.

The American journal of psychiatry·2026
Same author

Schizophrenia in Offspring of Holocaust Survivors: Intergenerational Effects of Preconception Parental Trauma Within the Jerusalem Perinatal Study.

The American journal of psychiatry·2026
Same author

Do Symptom Domains Have Similar Cellular Underpinnings Across Psychiatric Diagnoses: Evidence from 3D Hippocampal MR Spectroscopy.

bioRxiv : the preprint server for biology·2026
Same author

Sociodemographic, Financial, and Mental Health Predictors of Frequency of Dental Visits in Middle-Aged and Young Adults in the U.S.: Findings From the National Health Interview Survey 2023.

AJPM focus·2026
Same author

Quantifying direct genetic signal captured by principal component adjustment.

Proceedings of the National Academy of Sciences of the United States of America·2026

Related Experiment Video

Updated: Mar 20, 2026

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.9K

Socio-Genomics and Structural Competency.

Dalton Conley1, Dolores Malaspina2

  • 1Department of Sociology, Princeton University; and the National Bureau of Economic Research, 153 Wallace Hall, Princeton, NJ, 08540, USA. dconley@princeton.edu.

Journal of Bioethical Inquiry
|June 3, 2016
PubMed
Summary

Social and environmental factors significantly impact health burdens more than genetics alone. Integrating these social determinants into genetic risk models is crucial for better disease prediction and patient care.

Keywords:
EnvironmentEpigeneticGenotypeHealthMedical educationSocial genomicsStructural competency

More Related Videos

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms
10:41

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms

Published on: May 9, 2017

9.7K
In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

14.5K

Related Experiment Videos

Last Updated: Mar 20, 2026

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.9K
Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms
10:41

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms

Published on: May 9, 2017

9.7K
In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

14.5K

Area of Science:

  • Environmental Health
  • Genetics
  • Social Determinants of Health

Background:

  • Societal adversities and adverse developmental exposures contribute significantly to major health burdens.
  • Current genetic predictive models often overlook the substantial impact of social environmental factors on disease risk.
  • Patients increasingly share genetic information, yet social environmental influences on health outcomes are rarely discussed.

Purpose of the Study:

  • To integrate social environmental influences into genetic predictive models for disease risk assessment.
  • To highlight the critical role of social determinants in understanding complex diseases.
  • To advocate for enhanced healthcare provider education on genetic risks and societal adversities.

Main Methods:

  • Review and synthesis of existing literature on genetic predisposition and environmental impacts on health.
  • Development of a framework for integrating social environmental data into genetic risk prediction.
  • Analysis of the interplay between early life trauma, social disadvantage, and long-term health outcomes.

Main Results:

  • Social and environmental factors are demonstrably more significant contributors to health burdens than genotypic information alone.
  • Existing genetic models inadequately account for the profound influence of social determinants on disease susceptibility.
  • Early trauma and social disadvantage are linked to significant long-term health consequences.

Conclusions:

  • Integrating social environmental factors into genetic predictive models is essential for accurate disease risk assessment.
  • Healthcare providers require improved education to address genetic risks and the health consequences of societal adversities.
  • Optimizing patient care and prevention strategies necessitates a comprehensive understanding of both genetic and social determinants of health.