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Genomic Testing in The Paediatric Population: Ethical Considerations in Light of Recent Policy Statements

Ainsley J Newson1, Lisa Schonstein2

  • 1Centre for Values, Ethics and the Law in Medicine, School of Public Health, University of Sydney, Level 1, Medical Foundation Building, 92-4 Parramatta Road, NSW, 2006, Australia. ainsley.newson@sydney.edu.au.

Molecular Diagnosis & Therapy
|June 3, 2016
PubMed

Insights

Genomic testing in children raises unique ethical considerations. A child-focused, flexible approach guided by clinical questions is recommended for ethical genomic testing in pediatric patients.

Area of Science:

  • Bioethics
  • Genetics
  • Pediatric Medicine

Background:

  • Genomic testing is increasingly integrated into clinical practice and research.
  • Distinguishing genomics from genetics is crucial for ethical considerations.

Observation:

  • Ethical dilemmas in pediatric genomic testing require careful consideration.
  • Case studies highlight complex ethical issues in applying genomic technologies to children.

Findings:

  • Recent professional statements, like the 2015 ASHG position, offer guidance on genomic testing in children.
  • Synthesized bioethics literature provides a framework for decision-making in pediatric genomic testing.

Implications:

  • An adaptable, child-centered strategy for genomic testing in children is proposed.
  • The roles of a child's age and developing capacity in ethical decision-making warrant further examination.

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