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Laparoscopic versus percutaneous endoscopic gastrostomy placement in children: Results of a systematic review and
Nutnicha Suksamanapun1, Femke A Mauritz2, Josephine Franken1
1Department of Pediatric Surgery, Wilhelmina Children's Hospital, Utrecht, The Netherlands.
Insights
Percutaneous endoscopic gastrostomy (PEG) had more complications than laparoscopic-assisted gastrostomy (LAG) in children, including bowel injuries and dislodgements. More research is needed to confirm these findings for pediatric gastrostomy procedures.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Minimally Invasive Procedures
Background:
- Percutaneous endoscopic gastrostomy (PEG) and laparoscopic-assisted gastrostomy (LAG) are common procedures in pediatric patients.
- The comparative effectiveness and safety of PEG versus LAG in children require further investigation.
Purpose of the Study:
- To systematically review and compare the efficacy and safety of PEG and LAG in the pediatric population.
- To identify which gastrostomy procedure offers better outcomes regarding success rate, feeding efficacy, quality of life, gastroesophageal reflux, and complications.
Main Methods:
- A systematic review and meta-analysis was conducted following PRISMA guidelines.
- Included studies compared PEG and LAG in pediatric patients, analyzing outcomes such as success rate, feeding efficacy, quality of life, reflux, and complications.
Main Results:
- Five retrospective studies involving 550 PEG and 483 LAG placements were analyzed.
- PEG was associated with significantly higher rates of adjacent bowel injuries, early tube dislodgements, and complications requiring reintervention under general anesthesia compared to LAG.
- The overall completion rate and frequency of minor complications were similar between PEG and LAG.
Conclusions:
- Current evidence suggests PEG may be associated with a higher risk of specific complications in pediatric patients compared to LAG.
- The lack of well-designed randomized controlled trials necessitates caution in drawing definitive conclusions.
- Randomized controlled trials are crucial to establish best practices for gastrostomy placement in children.
Background:
Percutaneous endoscopic gastrostomy (PEG) and laparoscopic-assisted gastrostomy (LAG) are widely used in the paediatric population. The aim of this study was to determine which one of the two procedures is the most effective and safe method.
Methods:
This systematic review was conducted according to the preferred reporting items for systematic reviews and meta-analyses statement. Primary outcomes were success rate, efficacy of feeding, quality of life, gastroesophageal reflux and post-operative complications.
Results:
Five retrospective studies, comparing 550 PEG to 483 LAG placements in children, were identified after screening 2347 articles. The completion rate was similar for both procedures. PEG was associated with significantly more adjacent bowel injuries (P = 0.047), early tube dislodgements (P = 0.02) and complications that require reintervention under general anaesthesia (P < 0.001). Minor complications were equally frequent after both procedures.
Conclusions:
Because of the lack of well-designed studies, we have to be cautious in making definitive conclusions comparing PEG to LAG. To decide which type of gastrostomy placement is best practice in paediatric patients, randomised controlled trials comparing PEG to LAG are highly warranted.
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