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Endometrial sampling using the Mi Mark procedure as a primary routine: first year's experience.

M Uvebrant¹, H Bergström, G Hansson

¹Department of Obstetrics and Gynaecology, University of Göteborg, East Hospital, Sweden.

|March 1, 1989

Summary

The Mi Mark technique for endometrial sampling is accurate and acceptable for most patients, but may yield insufficient samples in women over 60. Further procedures are sometimes needed.

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Area of Science:

Gynecology
Diagnostic Procedures

Background:

Endometrial sampling is crucial for diagnosing gynecological conditions.
The Mi Mark technique offers a minimally invasive alternative to traditional methods like dilatation and curettage (D&C).

Purpose of the Study:

To evaluate the diagnostic accuracy and patient acceptability of the Mi Mark technique in routine practice.
To compare the Mi Mark technique with dilatation and curettage (D&C).

Main Methods:

A prospective study involving 736 patients undergoing endometrial sampling.
Comparison of Mi Mark technique with D&C, with secondary D&C performed for inadequate Mi Mark samples.

Main Results:

11% of pre-menopausal and 30% of post-menopausal Mi Mark specimens were inadequate for evaluation.

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Inadequate samples occurred in ~60% of women over 60, deeming the technique unsuitable for this group.

The Mi Mark technique could replace D&C in 47% of cases (excluding women over 60).

Endometrial cancers were detected in 2 cases following secondary D&C for inadequate Mi Mark samples.

8% of patients reported severe pain, while 93% would undergo the procedure again.

Conclusions:

The Mi Mark technique is acceptable and accurate for endometrial sampling when D&C is performed for inadequate specimens.
The technique is not suitable for women over 60 due to high rates of inadequate samples.
Mi Mark can replace D&C in a significant proportion of cases, improving patient experience.