Related Experiment Video
Updated: Mar 20, 2026

Standardized Model of Ventricular Fibrillation and Advanced Cardiac Life Support in Swine
Published on: January 30, 2020
Outcomes After Pediatric Out-of-Hospital Cardiopulmonary Interventions
Insights
Pediatric cardiopulmonary interventions by emergency medical services (EMS) show that infants under 1 year face higher death risks. EMS transport and dispatch times significantly impact survival and neurologic outcomes in children receiving CPI.
Area of Science:
- Pediatric Emergency Medicine
- Cardiopulmonary Resuscitation
- Out-of-Hospital Care
Background:
- Pediatric out-of-hospital cardiopulmonary interventions (CPI) are critical for young patients.
- Evaluating the effectiveness of Emergency Medical Services (EMS) in pediatric CPI is essential for improving outcomes.
Purpose of the Study:
- To assess the outcomes of pediatric patients who received out-of-hospital cardiopulmonary interventions (CPI) administered by emergency medical services (EMS).
Main Methods:
- Retrospective analysis of pediatric patients (≤18 years) receiving CPI by EMS from 2001-2008 in Utah.
- CPI defined as oxygenation, ventilation, or CPR with EMS transport.
- Regression analyses identified predictors of death and new neurologic dysfunction.
Main Results:
- Of 464 patients, 327 were alive on EMS arrival; 205 received CPI without CPR.
- 6% of these patients died in-hospital, and 6% were diagnosed with new neurologic dysfunction.
- Increased risk of death associated with age <1 year, shorter transport time, and longer dispatch time. Increased risk of neurologic dysfunction linked to pulselessness and CPR duration.
Conclusions:
- Infants under 1 year, shorter EMS transport, and longer dispatch times increase mortality risk in pediatric CPI.
- Pulselessness and need for CPR correlate with new neurologic dysfunction.
- Optimizing EMS interventions for infants <1 year undergoing CPI may enhance patient outcomes.
Objective:
The aim of the study was to evaluate outcomes after pediatric out-of-hospital cardiopulmonary interventions (CPIs) by emergency medical services (EMS).
Methods:
Children (age, ≤18 years) who received CPI by EMS from 2001 to 2008 were identified from the Utah Department of Health. Cardiopulmonary intervention was defined as oxygenation, ventilation or CPR, and transport to a hospital by EMS. Univariate and multivariable regression analyses evaluated associations between potential predictors and outcomes (death and new neurologic dysfunction).
Results:
A total of 464 patients (58% male) received EMS attention. For the 71% patients (327) who were alive on EMS arrival, 63% (205) received CPI without CPR. Of note, 6% (12) of these patients died after arrival to the hospital and new neurologic dysfunction was diagnosed in 6% (13). Among the 12 patients who died, 50% (6) were younger than 1 year.On multivariable regression analysis, factors associated with increased risk of death before and in-hospital are the following: age younger than 1 year (odds ratio [OR], 0.26; 95% confidence interval [CI], 0.17-0.39), shorter EMS transport time (OR, 0.94; 95% CI, 0.89-0.99), and longer EMS dispatch time (OR, 1.23; 95% CI, 1.08-1.40). Factors associated with increased risk of new neurologic dysfunction are the following: lack of pulse (OR, 0.14; 95% CI, 0.04-0.53), requiring CPR (OR, 6.15; 95% CI, 1.48-25.6), and CPR duration (OR, 1.20; 95% CI, 1.05-1.37).
Conclusions:
Age younger than 1 year, shorter transport time, and longer dispatch time were associated with increased risk of death. Being pulseless upon discovery and receiving CPR were associated with new neurologic dysfunction. Maximizing EMS transport interventions for patients younger than 1 year requiring CPI may improve patient outcomes.
More Related Videos
04:55Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model
Published on: May 26, 2023
10:55A Piglet Perinatal Asphyxia Model to Study Cardiac Injury and Hemodynamics after Cardiac Arrest, Resuscitation, and the Return of Spontaneous Circulation
Published on: January 13, 2023
Related Concept Videos
Cardiopulmonary Resuscitation I: Adult
Cardiopulmonary Resuscitation IV: Pharmacological Management
Cardiopulmonary Resuscitation II: ACLS Airway Management
Cardiopulmonary Resuscitation III: AED Use
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques
Acute Coronary Syndrome V: Nursing Management