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A plant DNA-binding protein that recognizes 5-methylcytosine residues
D L Zhang1, K C Ehrlich, P C Supakar
1Southern Regional Research Center, U.S. Department of Agriculture, New Orleans, Louisiana 70179.
Molecular and Cellular Biology
|March 1, 1989
Abstract:
A novel, 5-methylcytosine-specific, DNA-binding protein, DBP-m, has been identified in nuclear extracts of peas. DBP-m specifically recognizes 5-methylcytosine residues in DNA without appreciable DNA sequence specificity, unlike a mammalian DNA-binding protein (MDBP), which recognizes 5-methylcytosine residues but only in a related family of 14-base-pair sequences.