[Food-induced anaphylaxis - data from the anaphylaxis registry]

Area of Science:

• Allergy and Immunology
• Clinical Medicine
• Public Health

Background:

• Food allergy is a significant cause of anaphylaxis, a severe allergic reaction.
• Common food allergens differ between children and adults, with regional variations in rare triggers.
• Fatal anaphylaxis cases highlight the critical need for understanding and managing food allergies.

Purpose of the Study:

• To summarize common and rare food allergens causing anaphylaxis.
• To identify age-specific triggers for severe allergic reactions.
• To discuss the role of co-factors and long-term management strategies for food-induced anaphylaxis.

Main Methods:

• Analysis of data from an anaphylaxis registry.
• Review of reported cases of fatal anaphylaxis.
• Literature review on co-factors and management strategies.

Main Results:

• Hen's egg and milk are common triggers in young children; peanut and hazelnut in school children.
• Wheat, soy, celery, shellfish, and hazelnut are frequent triggers in adults.
• Fatal food-induced anaphylaxis occurred in 7 out of 17 registered cases; co-factors like physical activity and stress can influence severity.

Conclusions:

• Effective management of food-induced anaphylaxis requires prompt treatment and comprehensive long-term strategies.
• Patient education on allergen avoidance and co-factor awareness is crucial for preventing severe reactions.
• Further research is needed to fully elucidate the impact of co-factors on anaphylaxis severity.