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Engineering Paper-Based Sensors for Zika Virus
Robert J Meagher1, Oscar A Negrete1, Koen K Van Rompay2
1Sandia National Laboratories, Biotechnology and Bioengineering Department, Livermore, CA 94551, USA.
Trends in Molecular Medicine
|June 4, 2016
Abstract:
The emergence of Zika virus (ZIKV) infections in Latin America and Southeast Asia has created an urgent need for new, simple, yet sensitive, diagnostic tests. We highlight recent work using paper-based sensors coupled with CRISPR/Cas9 to detect ZIKV RNA as a new approach to achieve rapid development and deployment of field-ready diagnostics for emerging infectious diseases.
Keywords:
CRISPR/Cas9emerging infectious diseasesmolecular diagnosticspaper microfluidicstoehold sensors
