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Isolated tubercular hypoglossal nerve paralysis.

J S Thakur1, Naina Verma2, Shobha Mohindroo3

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Area of Science:

  • Neurology
  • Infectious Diseases
  • Otolaryngology

Background:

  • Hypoglossal nerve palsy is a known neurological condition.
  • Primary nasopharyngeal tuberculosis (TB) is an exceptionally rare etiology for neurological deficits.

Observation:

  • A 31-year-old female presented with headache and progressive right-sided tongue deviation.
  • Nasal endoscopy identified a nasopharyngeal mass; MRI showed a nasopharyngeal tumor.

Findings:

  • Histopathological examination confirmed tuberculosis (TB) as the cause of the nasopharyngeal mass.
  • The tumor was isointense on MRI, with no apparent involvement of the hypoglossal nerve or brain directly.

Implications:

  • This case underscores the importance of considering rare infectious etiologies in neurological presentations.
  • Understanding the pathogenesis of TB-induced cranial nerve palsies is crucial for timely diagnosis and management.