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Quality Control01:05

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Quality control is one of the three cyclical quality assurance activities that help keep a system under statistical control. Typical quality control activities include creating quality control charts, conducting proficiency testing, and documenting and archiving results.
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Strain improvement is a foundational strategy in industrial microbiology aimed at maximizing microbial productivity, particularly because natural isolates typically yield commercially valuable products in very low concentrations. Although optimizing the culture medium and environmental conditions can improve yields, these adjustments are inherently limited by the organism’s genetic potential. As a result, the focus shifts toward genetic modifications to enhance biosynthetic capacity. The...
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Laboratory services: regaining and maintaining control.

Graham R Lee1, Maria C Fitzgibbon1, Paula O'Shea2

  • 1Department of Clinical Biochemistry and Diagnostic Endocrinology, Mater Misericordiae University Hospital, Dublin, Ireland.

International Journal of Health Care Quality Assurance
|June 4, 2016
PubMed
Summary
This summary is machine-generated.

This study provides guidance for clinical laboratory staff on maintaining analytical performance through internal quality control (IQC) programs. It details methods for monitoring, troubleshooting, and regaining quality to ensure accurate patient test results.

Keywords:
Quality measuresQuality programmesRisk managementRoot cause analysisTotal quality management

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Area of Science:

  • Clinical Laboratory Science
  • Analytical Chemistry
  • Quality Management Systems

Background:

  • Maintaining high analytical performance is crucial in clinical laboratories for accurate patient diagnosis and treatment.
  • Internal Quality Control (IQC) programs are essential for monitoring and ensuring the reliability of laboratory testing.
  • Adherence to international accreditation requirements and best practices is vital for laboratory operations.

Purpose of the Study:

  • To outline strategies for maintaining and regaining analytical performance in clinical laboratories.
  • To provide guidance for laboratory staff on effective Internal Quality Control (IQC) program implementation.
  • To safeguard the medical purpose of patient test results through robust quality assurance.

Main Methods:

  • Utilizing prospective and retrospective analysis of IQC data.
  • Employing various software tools for performance monitoring at individual, multi-analyzer, and network levels.
  • Implementing systematic troubleshooting, risk assessment, and continuous quality improvement initiatives.

Main Results:

  • Development of approaches for monitoring analytical performance across different scales.
  • Recommendations for responding to IQC rule warnings, failures, and performance degradation.
  • Guidance on preventive measures and corrective actions to maintain analytical control.

Conclusions:

  • The proposed template aids laboratory personnel in optimal analytical performance monitoring and response to undesirable changes.
  • The template aligns with ISO 15189:2012 standards, integrating IQC, External Quality Assessment, and patient data.
  • Effective IQC programs and systematic quality management minimize potential patient harm.