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Related Concept Videos

Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

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Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid...
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First bacteraemic human infection with Escherichia albertii.

T J J Inglis1, A J Merritt1, N Bzdyl2

  • 1Department of Microbiology, PathWest Laboratory Medicine, Nedlands, Western Australia, Australia; School of Pathology and Laboratory Medicine, Faculty of Medicine, Dentistry and Health Sciences, University of Western Australia, Crawley, Western Australia, Australia.

New Microbes and New Infections
|June 4, 2016
PubMed
Summary

Escherichia albertii, a Gram-negative bacterium, caused a rare febrile infection and bloodstream invasion (bacteraemia) in an elderly woman. This highlights a new potential human pathogen in clinical settings.

Keywords:
BacteraemiaEscherichiabacterial identification methodsfacultative anaerobesgut microbiota

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Area of Science:

  • Microbiology
  • Infectious Diseases
  • Clinical Medicine

Background:

  • Escherichia albertii is a facultative anaerobic, Gram-negative bacterium.
  • This species has been previously isolated from human gastrointestinal infections and various wild bird species.

Observation:

  • A case of febrile infection linked to Escherichia albertii bacteraemia is presented.
  • The patient was a 76-year-old woman with a history of gastric dysplasia.

Findings:

  • This report details the first documented instance of Escherichia albertii causing bacteraemia in a human patient.
  • The infection presented with fever in the context of underlying gastric dysplasia.

Implications:

  • This finding expands the known clinical spectrum of Escherichia albertii infections in humans.
  • It underscores the importance of considering Escherichia albertii as a potential pathogen in immunocompromised or elderly patients.
  • Further research is warranted to understand the pathogenicity and epidemiology of Escherichia albertii in human infections.