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[Are hematologic reference values applicable to the healthy elderly?].

E C van Oosterhout, J Hermans, H L Haak

    Nederlands Tijdschrift Voor Geneeskunde
    |May 6, 1989
    PubMed
    Summary
    This summary is machine-generated.

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    Hematological reference ranges for elderly men may need adjustment. This study found lower hemoglobin and erythrocyte counts in healthy older men compared to standard ranges.

    Area of Science:

    • Gerontology
    • Hematology
    • Clinical Pathology

    Context:

    • Assessing the health of the elderly population requires accurate reference ranges for laboratory tests.
    • Established reference ranges may not fully account for physiological changes associated with aging in specific demographics.

    Purpose:

    • To examine the variability of hematological findings in healthy elderly individuals (65-90 years).
    • To compare these findings with existing reference ranges.
    • To determine if current reference ranges for specific hematological parameters are appropriate for elderly men.

    Summary:

    • Hematological parameters, including hemoglobin and erythrocyte counts, were analyzed in 80 men and 75 women aged 65-90.
    • Elderly men exhibited lower ranges for hemoglobin (7.4-10.5 mmol/l) and erythrocyte counts (3.8-5.5 x 10(12)/l) compared to established reference intervals (8.5-10.9 mmol/l and 4.4-6.0 x 10(12)/l).

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  • No discrepancies were observed in the hematological findings of elderly women.

    • Impact:

    • Suggests a potential need to revise reference limits for hemoglobin and erythrocyte counts in elderly men.
    • Highlights the importance of age- and sex-specific reference ranges in geriatric hematology.
    • Could influence diagnostic criteria and clinical interpretation of blood tests in older male populations.