Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Autoregulation of Blood Flow

Autoregulation of Blood Flow

Autoregulation mechanisms are characterized by their inherent capacity for self-regulation without necessitating specific nervous stimulation or endocrine control. These mechanisms facilitate the adjustment of blood flow and, therefore, perfusion specific to each tissue region. This self-regulation encompasses chemical signals and myogenic controls.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation....

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Timing of IABP initiation and its impact on outcomes in acute myocardial infarction with cardiogenic shock: insights from a bi-center retrospective study.

Clinical research in cardiology : official journal of the German Cardiac Society·2026

Same author

Hypothalamic orexigenic and anorexigenic neuropeptides in the rotenone model of Parkinson's disease.

Scientific reports·2026

Same author

Effect of Amorphous Silicates on the Neutralization of Tricalcium Aluminate Hexahydrate Relevant to Bauxite Residue Treatment.

Inorganic chemistry·2026

Same author

Assessing the impact of transcatheter edge-to-edge repair on reverse remodeling in secondary mitral regurgitation: a systematic review and meta-analysis.

Frontiers in cardiovascular medicine·2026

Same author

The influence of homogeneity on the stability assessment of reference materials.

Analytica chimica acta·2026

Same author

Photoassisted Chemical Transformation of Cu<sub>2</sub>O Nanooctahedra into Cu<sub>2</sub>S Quantum-Dot Superstructures: Structural and Photoelectrochemical Properties.

ACS materials Au·2025

Search research articles

Related Experiment Video

Updated: Mar 20, 2026

Author Spotlight: A Pharmacodissection Approach to Uncover Mechanisms in Cardiovascular Disease Risk Populations

Author Spotlight: A Pharmacodissection Approach to Uncover Mechanisms in Cardiovascular Disease Risk Populations

Published on: July 21, 2023

Altered microrheological parameters in Raynaud's phenomenon.

Judit Papp¹, Barbara Sandor¹, Andras Toth¹

¹1st Department of Medicine, University of Pecs, School of Medicine, Pecs, Hungary.

Clinical Hemorheology and Microcirculation

|June 4, 2016

Summary

Raynaud's phenomenon patients show increased red blood cell aggregation and decreased deformability, impacting microcirculation. These hemorheological changes, not linked to cold agglutinins or cryoglobulins, are key to understanding the condition.

Keywords:

Raynaud’s phenomenon cold agglutinin cryoglobulin erythrocyte deformability erythrocyte aggregation hemorheology viscosity

More Related Videos

A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology

A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology

Published on: February 7, 2015

Ultrasound Assessment of Flow-Mediated Dilation of the Brachial and Superficial Femoral Arteries in Rats

Ultrasound Assessment of Flow-Mediated Dilation of the Brachial and Superficial Femoral Arteries in Rats

Published on: November 3, 2016

Related Experiment Videos

Last Updated: Mar 20, 2026

Author Spotlight: A Pharmacodissection Approach to Uncover Mechanisms in Cardiovascular Disease Risk Populations

Author Spotlight: A Pharmacodissection Approach to Uncover Mechanisms in Cardiovascular Disease Risk Populations

Published on: July 21, 2023

A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology

A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology

Published on: February 7, 2015

Ultrasound Assessment of Flow-Mediated Dilation of the Brachial and Superficial Femoral Arteries in Rats

Ultrasound Assessment of Flow-Mediated Dilation of the Brachial and Superficial Femoral Arteries in Rats

Published on: November 3, 2016

Area of Science:

Vascular Biology
Hematology
Rheology

Background:

Raynaud's phenomenon involves episodic, painful attacks due to diminished blood supply in extremities.
Understanding the underlying hemorheological factors is crucial for managing this condition.

Purpose of the Study:

To investigate hemorheological parameters, cold agglutinins, and cryoglobulins in Raynaud's phenomenon patients.
To explore the relationship between these factors and the condition's pathophysiology.

Main Methods:

Blood samples from 74 Raynaud's patients and 58 healthy controls were analyzed.
Measurements included cold agglutinins, cryoglobulins, hematocrit, plasma and whole blood viscosity, red blood cell aggregation, and deformability.

Main Results:

Raynaud's patients exhibited significantly increased red blood cell aggregation and decreased deformability compared to controls.
No significant differences were found in hematocrit, plasma, or whole blood viscosity between groups.
Hemorheological profiles did not differ between patients positive or negative for cold agglutinins/cryoglobulins, nor between primary and secondary Raynaud's.

Conclusions:

Altered erythrocyte aggregation and deformability appear unfavorable in Raynaud's phenomenon.
These rheological changes may contribute to microcirculatory disturbances in affected individuals.