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The Human Thymus Is Enriched for Autoreactive B Cells

Magdalena B Rother1, Marco W J Schreurs1, Roel Kroek1

  • 1Department of Immunology, Erasmus Medical Center, University Medical Center Rotterdam, 3000 DR Rotterdam, the Netherlands; and.

Journal of Immunology (Baltimore, Md. : 1950)
|June 5, 2016
PubMed
Summary

Thymic B cells, crucial for T cell development, are primarily mature and autoreactive, presenting autoantigens to T cell progenitors during negative selection.

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