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Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
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Renal Corpuscle01:20

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Glomerular filtration rate (GFR) can be estimated from serum creatinine using the modification of diet in renal disease (MDRD) formula or the chronic kidney disease–epidemiology collaboration (CKD–EPI) equation. Both methods are widely used in clinical practice to assess kidney function and guide treatment decisions.The MDRD equation does not require weight or height measurements and is normalized to the body surface area of 1.73 m², considered the average adult surface area.
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Related Experiment Video

Updated: Mar 20, 2026

Assessment of Kidney Function in Mouse Models of Glomerular Disease
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Patient-Reported Outcomes in Glomerular Disease.

David T Selewski1, Aliza Thompson2, Sarrit Kovacs3

  • 1Division of Nephrology, Department of Pediatrics and Communicable Diseases, C.S. Mott Children's Hospital and.

Clinical Journal of the American Society of Nephrology : CJASN
|June 5, 2016
PubMed
Summary

Patient-reported outcomes (PROs) capture the patient experience in glomerular disease research and care. Utilizing PRO instruments can lead to better understanding and improved therapies tailored to patient needs.

Keywords:
Disease ManagementHumansPatient Outcome Assessmentglomerulonephritisglomerulopathykidney diseasepatient-centered outcomesquality of life

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Area of Science:

  • Nephrology
  • Patient-Reported Outcomes Research

Background:

  • The patient perspective is crucial for understanding and managing glomerular disease.
  • Systematic efforts are underway to capture and describe the patient experience in glomerular disease.
  • Patient-reported outcome (PRO) instruments offer a quantitative method to assess patient health status.

Purpose of the Study:

  • To provide an overview of PRO terminology and development.
  • To review available PRO instruments for glomerular disease.
  • To examine existing PRO data and identify opportunities for integration into clinical practice and research.

Main Methods:

  • Literature review of PRO instruments and data in glomerular disease.
  • Analysis of PRO development methodologies and terminology.
  • Identification of opportunities for PRO incorporation in clinical care and research.

Main Results:

  • Overview of PRO terminology and development methods provided.
  • Review of currently available PRO instruments suitable for glomerular disease.
  • Summary of existing PRO data and potential applications in glomerular disease research and care.

Conclusions:

  • Incorporating patient perspectives through PROs enhances understanding of glomerular disease.
  • PRO instruments facilitate quantitative assessment and comparison of patient experiences.
  • Integrating PROs into clinical care and research can lead to patient-centered therapies and improved outcomes.