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Asymptomatic Group A Streptococcus carriage in children with recurrent tonsillitis and tonsillar hypertrophy
Isabela P Olivetti Pontin1, Daniela Cristina Janolli Sanchez1, Renata Di Francesco1
1Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil.
Insights
Group A Streptococcus (GAS) is a common cause of tonsillitis in children. This study found an 18.1% GAS carriage rate in pediatric patients undergoing tonsillectomy, with no link to recurrent tonsillitis.
Area of Science:
- Pediatric Infectious Diseases
- Bacteriology
- Otolaryngology
Background:
- Group A Streptococcus (GAS) is the primary bacterial pathogen causing acute tonsillitis in pediatric populations.
- Chronic GAS carriage in children remains incompletely understood.
- This study investigated GAS prevalence in children undergoing tonsillectomy for specific indications.
Purpose of the Study:
- To determine the frequency of GAS detection in pediatric patients indicated for tonsillectomy.
- To explore potential correlations between GAS carriage and clinical factors such as age, sex, and history of recurrent tonsillitis.
- To compare GAS prevalence in children with adenotonsillar hypertrophy versus those with recurrent GAS infections.
Main Methods:
- A rapid antigen detection test was employed for GAS identification.
- Tonsil swabs were collected from seventy-two pediatric patients.
- Data analysis focused on GAS detection rates and associated demographic and clinical variables.
Main Results:
- The rapid antigen detection test yielded a positive result for GAS in 18.1% of the pediatric cohort.
- No significant association was observed between GAS detection and patient sex, age, or prior history of recurrent tonsillitis.
- GAS prevalence was comparable between children with recurrent tonsillitis and those with tonsillar hypertrophy.
Conclusions:
- The observed GAS carriage rate aligns with findings from previous research.
- The study did not establish a correlation between the GAS carrier state and the occurrence of recurrent tonsillitis in the studied pediatric population.
Background:
Group A Streptococcus (GAS) is the most important bacterial cause of acute tonsillitis in children. Some children are chronic GAS carriers, and this carriage is poorly understood. We determined the frequency of GAS detection using a rapid antigen detection test in pediatric patients with indications for tonsillectomy due to adenotonsillar hypertrophy or recurrent GAS infections.
Methods:
Seventy-two patients underwent a tonsil swab for a rapid antigen detection test.
Results:
The GAS rapid antigen detection test was positive in 18.1% of children. GAS was not associated with sex, age or previous history of recurrent tonsillitis. Also, the prevalence of GAS was similar between patients with either recurrent tonsillitis or tonsil hypertrophy.
Conclusion:
In our study, the GAS carriage rate was similar to other reports, and GAS carrier state was not correlated with recurrent tonsillitis.
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