Asymptomatic Group A Streptococcus carriage in children with recurrent tonsillitis and tonsillar hypertrophy

Isabela P Olivetti Pontin1, Daniela Cristina Janolli Sanchez1, Renata Di Francesco1

  • 1Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil.

Insights

Group A Streptococcus (GAS) is a common cause of tonsillitis in children. This study found an 18.1% GAS carriage rate in pediatric patients undergoing tonsillectomy, with no link to recurrent tonsillitis.

Area of Science:

  • Pediatric Infectious Diseases
  • Bacteriology
  • Otolaryngology

Background:

  • Group A Streptococcus (GAS) is the primary bacterial pathogen causing acute tonsillitis in pediatric populations.
  • Chronic GAS carriage in children remains incompletely understood.
  • This study investigated GAS prevalence in children undergoing tonsillectomy for specific indications.

Purpose of the Study:

  • To determine the frequency of GAS detection in pediatric patients indicated for tonsillectomy.
  • To explore potential correlations between GAS carriage and clinical factors such as age, sex, and history of recurrent tonsillitis.
  • To compare GAS prevalence in children with adenotonsillar hypertrophy versus those with recurrent GAS infections.

Main Methods:

  • A rapid antigen detection test was employed for GAS identification.
  • Tonsil swabs were collected from seventy-two pediatric patients.
  • Data analysis focused on GAS detection rates and associated demographic and clinical variables.

Main Results:

  • The rapid antigen detection test yielded a positive result for GAS in 18.1% of the pediatric cohort.
  • No significant association was observed between GAS detection and patient sex, age, or prior history of recurrent tonsillitis.
  • GAS prevalence was comparable between children with recurrent tonsillitis and those with tonsillar hypertrophy.

Conclusions:

  • The observed GAS carriage rate aligns with findings from previous research.
  • The study did not establish a correlation between the GAS carrier state and the occurrence of recurrent tonsillitis in the studied pediatric population.
Abstract

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