Related Experiment Video
Updated: Mar 20, 2026
04:24
Acupoint Application as a Traditional Chinese Medicine Treatment for Fatigue Associated with Chronic Obstructive Pulmonary Disease
Published on: September 5, 2025
1.4K
[Chronic fatigue syndrome: A new disorder?]
J-D de Korwin1, L Chiche2, I Banovic3
1Faculté de médecine, université de Lorraine, département de médecine interne et d'immunologie clinique, CHU de Nancy, hôpital de Brabois-BPC, rue du Morvan, 54511 Vandœuvre-lès-Nancy cedex, France.
La Revue De Medecine Interne
|June 5, 2016
Summary
Chronic Fatigue Syndrome (CFS) presents diagnostic and management challenges due to unclear pathophysiology. A new concept, Systemic Exertion Intolerance Disease, simplifies diagnosis and encourages research for this complex condition.
Area of Science:
- Medical Science
- Immunology
- Neurology
Background:
- Chronic Fatigue Syndrome (CFS) remains a debilitating and poorly understood condition over 30 years after its identification.
- Diagnostic difficulties and lack of standardized management contribute to patient suffering and physician confusion.
- The multifactorial pathophysiology involves infections, psychological factors, and persistent inflammatory, immunological, and muscular abnormalities.
Purpose of the Study:
- To review the current understanding of CFS pathophysiology.
- To introduce and analyze the new diagnostic concept of Systemic Exertion Intolerance Disease (SEID).
- To discuss the implications of SEID for patient management and future research.
Main Methods:
- Rigorous analysis of existing scientific data on CFS.
- Review of the proposed diagnostic criteria and conceptual framework for SEID.
- Comparative analysis of SEID with previous CFS and myalgic encephalomyelitis (ME) terminology.
Main Results:
- CFS pathophysiology is complex, involving immune, inflammatory, muscular, and neuroendocrine dysfunctions.
- The SEID concept offers a simplified diagnostic approach, moving away from previous terminologies.
- SEID acknowledges the central role of post-exertional malaise in the patient experience.
Conclusions:
- The SEID concept represents a significant shift in understanding and diagnosing CFS/ME.
- While it is premature to classify SEID as a distinct disease, it is a catalyst for improved patient recognition and research.
- Further research is needed to validate SEID and refine management strategies for patients with CFS.
Keywords:
Autoimmune diseasesChronic fatigue syndromeEncéphalomyélite myalgiqueFibromyalgiaFibromyalgieImmunologic disordersImmunopathologieInfectionsInflammationMaladies auto-immunesMyalgic encephalomyelitisSyndrome de fatigue chroniqueSyndrome d’intolérance systémique à l’effortSystemic exertion intolerance disease
Related Concept Videos
01:21Fatigue
982
Fatigue occurs when materials rupture under repeated or fluctuating loads, even at stress levels far below their static breaking strength. It typically results in brittle failure, even for ductile materials. It is a critical consideration in designing machines and structural components subjected to repetitive or varying loads. The nature of these loadings can range from fluctuating loads like unbalanced pump impellers causing vibrations to repeatedly bending a thin steel rod wire back and forth...
982
01:24Chronic Pancreatitis I: Introduction
851
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
851
01:24Muscle Recovery and Fatigue
4.7K
Muscle fatigue refers to the decline in a muscle's ability to maintain the force of contraction after prolonged activity. It primarily stems from changes within muscle fibers. Even before experiencing muscle fatigue, one may feel tired and have the urge to stop the activity. This response, known as central fatigue, occurs due to changes in the central nervous system, namely the brain and spinal cord. While there is no single mechanism that induces fatigue, it may serve as a protective...
4.7K
01:24Chronic Obstructive Pulmonary Disease
3.0K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
3.0K
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
4.0K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
4.0K
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
4.1K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
4.1K